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Carl Hennigan

👤 Person
978 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Anybody who wants to join on that, it'd be great to hear from you because it's a huge issue now.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Yeah, we're starting it because we put so much weight on a single model and yet daily all the data is changing, isn't it?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

How on earth do you end up joining models together like that?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Well, you don't.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

It should be a live platform.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

It shouldn't be a static production and saying, here's our model.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Once you've got the input to the model, you can produce outputs on a daily basis with updated data.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And you can keep producing that.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And what you want to see is how stable it looks.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And if it's not stable, for instance, the estimates are changing significantly on a daily basis.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So one day you've got 50,000 deaths, the next day you've got 20,000.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

You know you've got a problem.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And so you can't publish it at that point, but you can produce the information.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

That's a classic example of where we need a radically different approach.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

I think it's really interesting about prediction rules.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

We have to understand what they're really useful for.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

What are they useful for?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Well, what they're useful for is communicating information across different systems.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So, for instance, let's take the news score, which is a score you use to try and say, what's the chances of you're in primary care?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And I'm speaking to an ambulance driver and I'm trying to say, I'm worried about this patient.