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Carl Hennigan

👤 Person
978 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

But in somebody who's 95, who their sats are 94 all the time, you might go, well, actually, that's just what they are.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And that's where they are.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And actually, you wouldn't act on that person.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And so that's the problem with a one size fits all prediction.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Well, let's take the biggest disease in the world, cardiovascular disease, where we've done the most evidence and the most prediction rules and looked at it in so many ways.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

They're very interesting, but there's no evidence to show that if you use prediction rules, A, that they actually predict the people who actually have the disease, and B, using them improves overall mortality.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And I think you have to remember these sorts of things when you're trying to go, actually, if we just say, take this model and ship all these people in,

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Is that what you're actually going to do?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Well, then you work out, why do I have doctors?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Why do I have any in the process?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

They're not the decision-making tool.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

They are the communicating tool that allow us.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So when I use this new score, it's I've used it because I've already made my decision about this patient needs to go in hospital.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

I'm using my clinical skills, other information, where we are.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And you're right.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And what you want to know is, is this person likely to benefit from the next piece of management?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Now,

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Where's the evidence for that?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

There is none, is there?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So it's not just the prediction rule.