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Carl Hennigan

👤 Person
978 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Now, the problem is when you look at it, there are no pharmacological treatments right now that have been shown to work that actually improve your outcomes.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And that's where there's a huge sort of number of trials going on trying to reduce the uncertainties and answer questions about what we may use, particularly to reduce your viral load, but particularly to reduce the complications.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Yeah, no, I think it's a very interesting issue.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Before we get there, let's just step back a bit and think about what's happening in the infection.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

One of the problems here is we're seeing this emergence of supersized hospitals, of sucking people into hospitals and these big centres.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And we've got this 19-gale hospital happening in London, and we're going to send 4,000 people there.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

But if you look at the evidence of what's happening in Italy and Spain, as you bring people into hospital, it becomes a sort of super center for the infection.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

10% of all the infections in Spain are in health care workers.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Then you come into hospital.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

If you haven't got the infection, you're going to definitely get it.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So it becomes a vector of carrying on the infection.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So one of the things for us is to start to consider, is it an appropriate way to deal with everybody by bringing them into hospital?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Or can you reverse that policy and start to think about, actually, can you keep people in the home setting?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And if you did that, you could give them good advice.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

You could probably give them a pulse oximeter.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

You could give them a thermometer.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And you could have daily contact to understand what's going on, to watch out for those who deteriorate.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Because I think there are two important issues here.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

One is the deterioration into what we call viral pneumonia.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And viral pneumonia tends to be slow onset.