Carole Hemmelgarn
๐ค SpeakerAppearances Over Time
Podcast Appearances
Maybe that's because experimentation will inevitably produce a lot of failure. I mean, that's the point. And most of us just don't want to fail at all, even if it's in the service of long-term success. So let's see if we can't adjust our focus here. Let's talk about real experimentation.
Maybe that's because experimentation will inevitably produce a lot of failure. I mean, that's the point. And most of us just don't want to fail at all, even if it's in the service of long-term success. So let's see if we can't adjust our focus here. Let's talk about real experimentation.
And for that, we will need not another social scientist like John Van Rienen or Amy Edmondson, as capable as they are, but an actual science scientist. Here is one of the most acclaimed scientists of the modern era.
And for that, we will need not another social scientist like John Van Rienen or Amy Edmondson, as capable as they are, but an actual science scientist. Here is one of the most acclaimed scientists of the modern era.
And for that, we will need not another social scientist like John Van Rienen or Amy Edmondson, as capable as they are, but an actual science scientist. Here is one of the most acclaimed scientists of the modern era.
And if I say to you, Bob, what kind of scientist are you exactly? How do you answer that question?
And if I say to you, Bob, what kind of scientist are you exactly? How do you answer that question?
And if I say to you, Bob, what kind of scientist are you exactly? How do you answer that question?
Langer holds more than 1,500 patents, including those that are pending. He runs the world's largest biomedical engineering lab at MIT, and he is one of the world's most highly cited biotech researchers. He also played a role in the founding of dozens of biotech firms, including Moderna, which produced one of the most effective COVID vaccines.
Langer holds more than 1,500 patents, including those that are pending. He runs the world's largest biomedical engineering lab at MIT, and he is one of the world's most highly cited biotech researchers. He also played a role in the founding of dozens of biotech firms, including Moderna, which produced one of the most effective COVID vaccines.
Langer holds more than 1,500 patents, including those that are pending. He runs the world's largest biomedical engineering lab at MIT, and he is one of the world's most highly cited biotech researchers. He also played a role in the founding of dozens of biotech firms, including Moderna, which produced one of the most effective COVID vaccines.
One thing Langer is particularly known for is drug delivery. That is developing and refining how a given drug is delivered and absorbed at the cellular level. A time-release drug, for instance, is the sort of thing we take for granted today, but it took a while to get there.
One thing Langer is particularly known for is drug delivery. That is developing and refining how a given drug is delivered and absorbed at the cellular level. A time-release drug, for instance, is the sort of thing we take for granted today, but it took a while to get there.
One thing Langer is particularly known for is drug delivery. That is developing and refining how a given drug is delivered and absorbed at the cellular level. A time-release drug, for instance, is the sort of thing we take for granted today, but it took a while to get there.
One problem Langer worked on back in the 1970s was finding a drug delivery system that would prevent the abnormal growth of blood vessels. The chemical that inhibits the growth is quite large by biological standards. And there was consensus at the time that a time release wouldn't work on large molecules.
One problem Langer worked on back in the 1970s was finding a drug delivery system that would prevent the abnormal growth of blood vessels. The chemical that inhibits the growth is quite large by biological standards. And there was consensus at the time that a time release wouldn't work on large molecules.
One problem Langer worked on back in the 1970s was finding a drug delivery system that would prevent the abnormal growth of blood vessels. The chemical that inhibits the growth is quite large by biological standards. And there was consensus at the time that a time release wouldn't work on large molecules.
But as Langer once put it, I didn't know you couldn't do it because I hadn't read the literature. So he ran experiment after experiment after experiment before finally developing a recipe that worked. Decades later, thanks to all that failure, his discovery played a key role in how Moderna used messenger RNA to create its COVID vaccine.
But as Langer once put it, I didn't know you couldn't do it because I hadn't read the literature. So he ran experiment after experiment after experiment before finally developing a recipe that worked. Decades later, thanks to all that failure, his discovery played a key role in how Moderna used messenger RNA to create its COVID vaccine.
But as Langer once put it, I didn't know you couldn't do it because I hadn't read the literature. So he ran experiment after experiment after experiment before finally developing a recipe that worked. Decades later, thanks to all that failure, his discovery played a key role in how Moderna used messenger RNA to create its COVID vaccine.