Casey Means, MD
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Podcast Appearances
And there was an amazing Lancet paper from a couple of years ago that showed that if we just got on top of some of the basic modifiable factors of our metabolic health, we could slash Alzheimer's rates from happening.
And there was an amazing Lancet paper from a couple of years ago that showed that if we just got on top of some of the basic modifiable factors of our metabolic health, we could slash Alzheimer's rates from happening.
And there was an amazing Lancet paper from a couple of years ago that showed that if we just got on top of some of the basic modifiable factors of our metabolic health, we could slash Alzheimer's rates from happening.
So, you know, I think, yeah, fundamentally, it's one more branch on the tree that is rooted in this metabolic dysfunction in our body, which is fundamentally rooted in three processes that uniquely really hurt the brain, which is oxidative stress, mitochondrial dysfunction and chronic inflammation. These are the three hallmarks of metabolic dysfunction.
So, you know, I think, yeah, fundamentally, it's one more branch on the tree that is rooted in this metabolic dysfunction in our body, which is fundamentally rooted in three processes that uniquely really hurt the brain, which is oxidative stress, mitochondrial dysfunction and chronic inflammation. These are the three hallmarks of metabolic dysfunction.
So, you know, I think, yeah, fundamentally, it's one more branch on the tree that is rooted in this metabolic dysfunction in our body, which is fundamentally rooted in three processes that uniquely really hurt the brain, which is oxidative stress, mitochondrial dysfunction and chronic inflammation. These are the three hallmarks of metabolic dysfunction.
And the brain is so sensitive and such a complex, high processing power organ that these core cellular disturbances that make up metabolic dysfunction, which are caused by our environment and cannot really be addressed with drugs, mitochondrial dysfunction, oxidative stress, chronic inflammation, they're showing up so prominently in the brain.
And the brain is so sensitive and such a complex, high processing power organ that these core cellular disturbances that make up metabolic dysfunction, which are caused by our environment and cannot really be addressed with drugs, mitochondrial dysfunction, oxidative stress, chronic inflammation, they're showing up so prominently in the brain.
And the brain is so sensitive and such a complex, high processing power organ that these core cellular disturbances that make up metabolic dysfunction, which are caused by our environment and cannot really be addressed with drugs, mitochondrial dysfunction, oxidative stress, chronic inflammation, they're showing up so prominently in the brain.
You were talking about this with Max Lugavere. Yeah. Max Lugavere.
You were talking about this with Max Lugavere. Yeah. Max Lugavere.
You were talking about this with Max Lugavere. Yeah. Max Lugavere.
Well, this is coming out every day. We're hearing about a new premier researcher who's published hundreds of papers in their field who literally are... Western blots are one of these things you see in scientific papers that basically show you protein levels. Yeah.
Well, this is coming out every day. We're hearing about a new premier researcher who's published hundreds of papers in their field who literally are... Western blots are one of these things you see in scientific papers that basically show you protein levels. Yeah.
Well, this is coming out every day. We're hearing about a new premier researcher who's published hundreds of papers in their field who literally are... Western blots are one of these things you see in scientific papers that basically show you protein levels. Yeah.
copied and pasted Western blots in like papers across their career, like just made up data that then has served as foundational dogma for future research. So you think about the ripple effect.
copied and pasted Western blots in like papers across their career, like just made up data that then has served as foundational dogma for future research. So you think about the ripple effect.
copied and pasted Western blots in like papers across their career, like just made up data that then has served as foundational dogma for future research. So you think about the ripple effect.
Yeah. And so this but this is it really gets back to the core problem that's above all the problems, which is an incentive problem. Like it's a simple economic incentive problem that's basically causing all these problems. And I think it's that what we're striving for in this country is ultimately economic growth and value. That is what we care about.
Yeah. And so this but this is it really gets back to the core problem that's above all the problems, which is an incentive problem. Like it's a simple economic incentive problem that's basically causing all these problems. And I think it's that what we're striving for in this country is ultimately economic growth and value. That is what we care about.