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Charan Ranganath

๐Ÿ‘ค Speaker
3063 total appearances

Appearances Over Time

Podcast Appearances

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And so you're basically using water, the water molecules in the brain as a tracer, so to speak. And part of it in fMRI is the fact that these magnetic fields that you mess with by manipulating these radio frequency pulses and the static field, and you have things called gradients which change the strength of the magnetic field in different parts of the head.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And so you're basically using water, the water molecules in the brain as a tracer, so to speak. And part of it in fMRI is the fact that these magnetic fields that you mess with by manipulating these radio frequency pulses and the static field, and you have things called gradients which change the strength of the magnetic field in different parts of the head.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So we tweak them in different ways, but the basic idea that we use in fMRI is that blood is flowing to the brain. And when you have blood that doesn't have oxygen on it, it's a little bit more magnetizable than blood that does, because you have hemoglobin that carries the oxygen, the iron, basically, in the blood that makes it red.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So we tweak them in different ways, but the basic idea that we use in fMRI is that blood is flowing to the brain. And when you have blood that doesn't have oxygen on it, it's a little bit more magnetizable than blood that does, because you have hemoglobin that carries the oxygen, the iron, basically, in the blood that makes it red.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So we tweak them in different ways, but the basic idea that we use in fMRI is that blood is flowing to the brain. And when you have blood that doesn't have oxygen on it, it's a little bit more magnetizable than blood that does, because you have hemoglobin that carries the oxygen, the iron, basically, in the blood that makes it red.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And so that hemoglobin, when it's deoxygenated, actually has different magnetic field properties than when it has oxygen. And it turns out when you have an increase in local activity in some part of the brain, the blood flows there. And as a result, you get a lower concentration of hemoglobin that is not oxygenated. And then that gives you more signal.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And so that hemoglobin, when it's deoxygenated, actually has different magnetic field properties than when it has oxygen. And it turns out when you have an increase in local activity in some part of the brain, the blood flows there. And as a result, you get a lower concentration of hemoglobin that is not oxygenated. And then that gives you more signal.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And so that hemoglobin, when it's deoxygenated, actually has different magnetic field properties than when it has oxygen. And it turns out when you have an increase in local activity in some part of the brain, the blood flows there. And as a result, you get a lower concentration of hemoglobin that is not oxygenated. And then that gives you more signal.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So I gave you, I think I sent you a gif, as you like to say.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So I gave you, I think I sent you a gif, as you like to say.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

So I gave you, I think I sent you a gif, as you like to say.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

We could have called it a stern rebuke, perhaps.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

We could have called it a stern rebuke, perhaps.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

We could have called it a stern rebuke, perhaps.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

This would be basically a whole movie of fMRI data. And so when you look at it, it's not very impressive. It looks like these very pixelated maps of the brain, but it's mostly kind of like white. But these tiny changes in the intensity of those signals that you probably wouldn't be able to visually perceive, like about 1%, can be statistically very, very large effects for us.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

This would be basically a whole movie of fMRI data. And so when you look at it, it's not very impressive. It looks like these very pixelated maps of the brain, but it's mostly kind of like white. But these tiny changes in the intensity of those signals that you probably wouldn't be able to visually perceive, like about 1%, can be statistically very, very large effects for us.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

This would be basically a whole movie of fMRI data. And so when you look at it, it's not very impressive. It looks like these very pixelated maps of the brain, but it's mostly kind of like white. But these tiny changes in the intensity of those signals that you probably wouldn't be able to visually perceive, like about 1%, can be statistically very, very large effects for us.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And that allows us to see, hey, there's an increase in activity in some part of the brain when I'm doing some tasks like trying to remember something. And I can use those changes to even predict, is a person going to remember this later or not? And the coolest thing that people have done is to decode what people are remembering from the patterns of activity.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And that allows us to see, hey, there's an increase in activity in some part of the brain when I'm doing some tasks like trying to remember something. And I can use those changes to even predict, is a person going to remember this later or not? And the coolest thing that people have done is to decode what people are remembering from the patterns of activity.

Lex Fridman Podcast
#430 โ€“ Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories

And that allows us to see, hey, there's an increase in activity in some part of the brain when I'm doing some tasks like trying to remember something. And I can use those changes to even predict, is a person going to remember this later or not? And the coolest thing that people have done is to decode what people are remembering from the patterns of activity.