Charan Ranganath

I believe – and my colleagues do. I wrote a big paper with Howard – the late Howard Eichenbaum and Andy Olenas on this who – from Davis. And we believe that it's about linking various experiences to a context. And what I mean by that is you've got information about smell, high-level vision, high-level semantic knowledge information, right?

And the hippocampus' wiring is really set up to not understand what's going on. So the late David Morrow's pioneer in computational neuroscience proposed that what the hippocampus is about is what he called simple memory. It's basically saying... I know Andy Huberman. Sorry, is that okay?

And the hippocampus' wiring is really set up to not understand what's going on. So the late David Morrow's pioneer in computational neuroscience proposed that what the hippocampus is about is what he called simple memory. It's basically saying... I know Andy Huberman. Sorry, is that okay?

And the hippocampus' wiring is really set up to not understand what's going on. So the late David Morrow's pioneer in computational neuroscience proposed that what the hippocampus is about is what he called simple memory. It's basically saying... I know Andy Huberman. Sorry, is that okay?

You would understand. So I know Andy Huberman, right? But to have a memory of this moment that's separate from, let's say, I saw you at some neuroscience retreat when you were in grad school, I have to have some part of the brain that doesn't know who you are to some extent, right? Because I got to keep them separate.

You would understand. So I know Andy Huberman, right? But to have a memory of this moment that's separate from, let's say, I saw you at some neuroscience retreat when you were in grad school, I have to have some part of the brain that doesn't know who you are to some extent, right? Because I got to keep them separate.

You would understand. So I know Andy Huberman, right? But to have a memory of this moment that's separate from, let's say, I saw you at some neuroscience retreat when you were in grad school, I have to have some part of the brain that doesn't know who you are to some extent, right? Because I got to keep them separate.

And so there are – the hippocampus, what it will do is it will form a memory that's not an Andy Huberman memory. It's an Andy in this place at this time in this context. And that's what allows it to support what's called episodic memory, which is your ability to say, I went to Washington, D.C. once and I remember going to the Smithsonian.

And so there are – the hippocampus, what it will do is it will form a memory that's not an Andy Huberman memory. It's an Andy in this place at this time in this context. And that's what allows it to support what's called episodic memory, which is your ability to say, I went to Washington, D.C. once and I remember going to the Smithsonian.

And so there are – the hippocampus, what it will do is it will form a memory that's not an Andy Huberman memory. It's an Andy in this place at this time in this context. And that's what allows it to support what's called episodic memory, which is your ability to say, I went to Washington, D.C. once and I remember going to the Smithsonian.

as opposed to your knowledge about what generally happens in Washington, D.C. Oh, the president's there. Oh, that's where a lot of politics happen. Oh, the Smithsonian is a place in D.C. It's a memory of your being there at a particular place and time.

as opposed to your knowledge about what generally happens in Washington, D.C. Oh, the president's there. Oh, that's where a lot of politics happen. Oh, the Smithsonian is a place in D.C. It's a memory of your being there at a particular place and time.

as opposed to your knowledge about what generally happens in Washington, D.C. Oh, the president's there. Oh, that's where a lot of politics happen. Oh, the Smithsonian is a place in D.C. It's a memory of your being there at a particular place and time.

Now, there's other parts of the brain that allow you to associate that information in a meaningful way and to be able to actually expand on that context and create these narratives and these stories about it. And where the prefrontal cortex comes in, and it's a huge area, it's about one-third of the primate brain. So it's just massive.

Now, there's other parts of the brain that allow you to associate that information in a meaningful way and to be able to actually expand on that context and create these narratives and these stories about it. And where the prefrontal cortex comes in, and it's a huge area, it's about one-third of the primate brain. So it's just massive.

Now, there's other parts of the brain that allow you to associate that information in a meaningful way and to be able to actually expand on that context and create these narratives and these stories about it. And where the prefrontal cortex comes in, and it's a huge area, it's about one-third of the primate brain. So it's just massive.

There are a lot of people who go, well, there's a bunch of different areas and I'll do different things. And I subscribe to the view that that is very true. And at the same time, there's a global function of the prefrontal cortex. which is what's called cognitive control.

There are a lot of people who go, well, there's a bunch of different areas and I'll do different things. And I subscribe to the view that that is very true. And at the same time, there's a global function of the prefrontal cortex. which is what's called cognitive control.

There are a lot of people who go, well, there's a bunch of different areas and I'll do different things. And I subscribe to the view that that is very true. And at the same time, there's a global function of the prefrontal cortex. which is what's called cognitive control.

It's this ability to say, I'm going to regulate my movements and I'm going to regulate my perceptions and my thoughts based on what's important to me in terms of this higher order goal, right? So when I've tested, for instance, patients with prefrontal lesions, I'm sure Mark Desposito talked to you about this,