Charan Ranganath

And it's to the point where she'll not exercise, even though she's a very active dog. She'll stop on a walk if she hears a garbage truck anywhere. And so it's a very low dose. And I'm not necessarily saying go drug your dogs.

But I'm just saying that the story that I've heard is that you get this period of plasticity where you can kind of rewrite some of these behavioral patterns and make them more open to training and so forth. And so it doesn't even have to be a permanent thing, right?

But I'm just saying that the story that I've heard is that you get this period of plasticity where you can kind of rewrite some of these behavioral patterns and make them more open to training and so forth. And so it doesn't even have to be a permanent thing, right?

But I'm just saying that the story that I've heard is that you get this period of plasticity where you can kind of rewrite some of these behavioral patterns and make them more open to training and so forth. And so it doesn't even have to be a permanent thing, right?

And I think a lot of these things like you're talking about, learned helplessness studies, probably transient effects of not being on it for years or something. Mm-hmm. But it's not very effective in terms of SSRIs. But psilocybin and psychedelics have shown a lot of promise as being bigger effects, right? And these produce massive plasticity.

And I think a lot of these things like you're talking about, learned helplessness studies, probably transient effects of not being on it for years or something. Mm-hmm. But it's not very effective in terms of SSRIs. But psilocybin and psychedelics have shown a lot of promise as being bigger effects, right? And these produce massive plasticity.

And I think a lot of these things like you're talking about, learned helplessness studies, probably transient effects of not being on it for years or something. Mm-hmm. But it's not very effective in terms of SSRIs. But psilocybin and psychedelics have shown a lot of promise as being bigger effects, right? And these produce massive plasticity.

There's two things I think that are really interesting about it. By the way, Davis, I will just say I'm biased, but it's one of the – top three places in the world for learning and memory research. So next door neighbor, David Olson, it turns out, is studying psychedelic effects on plasticity.

There's two things I think that are really interesting about it. By the way, Davis, I will just say I'm biased, but it's one of the – top three places in the world for learning and memory research. So next door neighbor, David Olson, it turns out, is studying psychedelic effects on plasticity.

There's two things I think that are really interesting about it. By the way, Davis, I will just say I'm biased, but it's one of the – top three places in the world for learning and memory research. So next door neighbor, David Olson, it turns out, is studying psychedelic effects on plasticity.

And, you know, so he really emphasizes that there's these massive neurotrophic factors, BDNF, like all these factors that are going on that are promoting plasticity. And, you know, for people who've taken them, that's what they report is that there's this period of integration afterwards where your brain's just like... you know, you could feel it. Everything.

And, you know, so he really emphasizes that there's these massive neurotrophic factors, BDNF, like all these factors that are going on that are promoting plasticity. And, you know, for people who've taken them, that's what they report is that there's this period of integration afterwards where your brain's just like... you know, you could feel it. Everything.

And, you know, so he really emphasizes that there's these massive neurotrophic factors, BDNF, like all these factors that are going on that are promoting plasticity. And, you know, for people who've taken them, that's what they report is that there's this period of integration afterwards where your brain's just like... you know, you could feel it. Everything.

That's right. It opens up like significant opportunities for reshaping. But the second part of it, which maybe I think is really interesting, is there is also a dissociative element of these drugs. So ketamine isn't a psychedelic, but I think there are some interesting plasticity effects and definitely produces this dissociative element too.

That's right. It opens up like significant opportunities for reshaping. But the second part of it, which maybe I think is really interesting, is there is also a dissociative element of these drugs. So ketamine isn't a psychedelic, but I think there are some interesting plasticity effects and definitely produces this dissociative element too.

That's right. It opens up like significant opportunities for reshaping. But the second part of it, which maybe I think is really interesting, is there is also a dissociative element of these drugs. So ketamine isn't a psychedelic, but I think there are some interesting plasticity effects and definitely produces this dissociative element too.

But with psychedelics, there's often a major perspective shift. Perspective is hugely important for memory because a lot of our sense of the emotional impact of our memory is based on a perspective that we adopt when we remember. Research has shown that you can take the same encoding event Meaning like I tell you a story – let's just take a very simple thing.

But with psychedelics, there's often a major perspective shift. Perspective is hugely important for memory because a lot of our sense of the emotional impact of our memory is based on a perspective that we adopt when we remember. Research has shown that you can take the same encoding event Meaning like I tell you a story – let's just take a very simple thing.

But with psychedelics, there's often a major perspective shift. Perspective is hugely important for memory because a lot of our sense of the emotional impact of our memory is based on a perspective that we adopt when we remember. Research has shown that you can take the same encoding event Meaning like I tell you a story – let's just take a very simple thing.

Very – I give you a story and it's like I tell you now viewed from the perspective of someone else and you're trying to remember it. You can remember things that you didn't remember the first time around. Changing your perspective can literally change what you remember. It can also change the narrative that you produce.