Charles Piller

There's clinical trials going on right now to see if that idea might be one of great importance.

And I think within the next couple of years, we're going to see

some evidence to suggest whether it is or not so i'm very hopeful about that adding new information to the field that could be beneficial the other is glp-1 inhibitors these are the new seemingly magical drugs that are used for weight loss and for diabetes and now a raft of other ailments

that have taken the world by storm over the last few years.

And they are also being tested as a possible preventive or treatment for Alzheimer's disease.

And very soon, even perhaps by the end of this year or early next year,

We're going to have the initial reading of a big clinical trial associated with GLP-1 inhibitors that will have some, I think, some interesting results to see whether they're heading down a path that could be beneficial.

And so these are the kind of scientific projects that give me a lot of hope and a lot of belief that science is vast.

much of it has not been corrupted.

Much of the set of ideas behind the brain and neuroscience and Alzheimer's disease, I think will bear fruit eventually in ways that can really be hopeful for patients.

And in the meantime, we also have the kind of hopeful quality of, again, living our best lives in ways that could help us forestall or prevent

Terrific question, John.

It's been a really difficult journey because I believe deeply in science and the scientific method.

I believe that it's one of the greatest, most important developments in human thinking historically.

We have reaped enormous benefits from it in medicine and in many other fields, of course.

That said, I think the scientific method teaches us that you can't fake information ultimately and get away with it because science is what they call self-correcting.

And what that means is that false information will eventually be

discovered, uncovered, and corrected by new experimentation.

The problem that I see in science is that because of difficulties in the journals, the funders, the universities,

and the regulators of science, all four of those important scientific institutions have deep flaws that have been created the conditions where problems in science, either corruption or just simple error or simple misunderstandings that are part of the scientific research process are being allowed to remain in the record and to skew thinking in the field for much longer than they need to be.