Charles Piller
π€ SpeakerAppearances Over Time
Podcast Appearances
And why hasn't the FDA stopped the trials if that was going on?
And why hasn't the FDA stopped the trials if that was going on?
I think there's a kind of complacency in certain ways in which the agency operates. I think also that there is such a desperate hunger and a sense of real desperation in the community of patients and family members who are living with Alzheimer's to have some sort of drug, some sort of remedy that can at least allay some of the worst cognitive symptoms.
I think there's a kind of complacency in certain ways in which the agency operates. I think also that there is such a desperate hunger and a sense of real desperation in the community of patients and family members who are living with Alzheimer's to have some sort of drug, some sort of remedy that can at least allay some of the worst cognitive symptoms.
I think there's a kind of complacency in certain ways in which the agency operates. I think also that there is such a desperate hunger and a sense of real desperation in the community of patients and family members who are living with Alzheimer's to have some sort of drug, some sort of remedy that can at least allay some of the worst cognitive symptoms.
It's very, very hard for the agency to resist the pressure that they're feeling from drug companies, from patient representatives, from the entire world to try to come up with approved drugs that can be used to help solve this terrible problem that we have with Alzheimer's.
It's very, very hard for the agency to resist the pressure that they're feeling from drug companies, from patient representatives, from the entire world to try to come up with approved drugs that can be used to help solve this terrible problem that we have with Alzheimer's.
It's very, very hard for the agency to resist the pressure that they're feeling from drug companies, from patient representatives, from the entire world to try to come up with approved drugs that can be used to help solve this terrible problem that we have with Alzheimer's.
I also don't see how it's valuable to manipulate or create data in the basic sciences step, then do it with the phase one trials when you know at some point the other shoe is going to drop and it would be found out that the medication is not as effective. Are scientists who engage in this type of behavior hoping that
I also don't see how it's valuable to manipulate or create data in the basic sciences step, then do it with the phase one trials when you know at some point the other shoe is going to drop and it would be found out that the medication is not as effective. Are scientists who engage in this type of behavior hoping that
I also don't see how it's valuable to manipulate or create data in the basic sciences step, then do it with the phase one trials when you know at some point the other shoe is going to drop and it would be found out that the medication is not as effective. Are scientists who engage in this type of behavior hoping that
maybe getting past the first stage will get them ultimately where they can prove truly that their medicine or treatment works. Do they have true belief in themselves or are they usually full on playing one of these games of let's make as much money as possible?
maybe getting past the first stage will get them ultimately where they can prove truly that their medicine or treatment works. Do they have true belief in themselves or are they usually full on playing one of these games of let's make as much money as possible?
maybe getting past the first stage will get them ultimately where they can prove truly that their medicine or treatment works. Do they have true belief in themselves or are they usually full on playing one of these games of let's make as much money as possible?
Yeah, it's tough. I mean, I'm not a psychologist and I don't play one on TV, so I can't really answer for sure what's going on in their minds. But what I can say is that you have a situation where historically it's been pretty easy to get away with falsifying data. And so there are many people who will roll the dice on it and reap the rewards.
Yeah, it's tough. I mean, I'm not a psychologist and I don't play one on TV, so I can't really answer for sure what's going on in their minds. But what I can say is that you have a situation where historically it's been pretty easy to get away with falsifying data. And so there are many people who will roll the dice on it and reap the rewards.
Yeah, it's tough. I mean, I'm not a psychologist and I don't play one on TV, so I can't really answer for sure what's going on in their minds. But what I can say is that you have a situation where historically it's been pretty easy to get away with falsifying data. And so there are many people who will roll the dice on it and reap the rewards.
And so even in a situation like the one you're describing, again, going back to Cassava Sciences for a moment, what you have is a situation where there was apparent image doctoring going on from the very beginning. apparent flaws in the thinking of this entire process from beginning to end, apparent other kinds of improper activities at the company.
And so even in a situation like the one you're describing, again, going back to Cassava Sciences for a moment, what you have is a situation where there was apparent image doctoring going on from the very beginning. apparent flaws in the thinking of this entire process from beginning to end, apparent other kinds of improper activities at the company.
And so even in a situation like the one you're describing, again, going back to Cassava Sciences for a moment, what you have is a situation where there was apparent image doctoring going on from the very beginning. apparent flaws in the thinking of this entire process from beginning to end, apparent other kinds of improper activities at the company.