Chris Masterjohn

Yeah, and I think one thing that I think we should talk about today is I've been in nutrition research for 21 years, and I think the crowning thesis of my work so far is that we really want to be thinking about mitochondrial function at the root of all health and disease.

And so I think an interesting way to see sleep is it's like, why do we have to sleep eight hours a night?

And I think with dreaming, there's obviously other things going on there.

But deep sleep, one of the primary things that's happening is you need to give your mitochondria a rest because your mitochondria are what produce all the energy that you need for sleep.

for producing everything in your body, for maintaining it, for repairing it, and for distributing it properly and for keeping it going across the lifespan.

And so your mitochondria are going to essentially take a nap, take a rest.

They don't go off because you die, but they really turn down the volume of the work they're doing.

But then you take your metabolic rate way lower than that.

And so you can build up the reserves of energy that you had used up the day before.

And so that can explain a lot of recent findings that are coming out as well, because there was that recent study where they looked at sleep deprivation with creatine supplementation.

And so they randomized people to either drink a placebo drink or drink 20 grams of creatine through the night.

And they kept them awake all night, and they had them do brain puzzle quizzes.

And when the subjects were getting the 20 grams of creatine, they did way better on the brain puzzles, but they also complained about being tired a lot less.

And so the conclusion is creatine is somehow acutely preventing your brain from suffering more.

during sleep deprivation.

And the rationale there is mitochondria are the powerhouse of the cell or the power plant that's producing the energy.

Creatine is like the power grid, and it distributes that energy throughout the cell.

And so if the purpose of sleep is to restore the energy that you used up, but then you intervene by putting creatine in there, now you can keep that energy going and you can go more hours before you need to get rest and restore that energy because you've

increased your capacity to distribute it.

Yeah, the sleep thing was in the last year.