Chris Masterjohn

So I do think that's interesting that it does make you wonder if you could skip leg day.

I don't advocate skipping leg day.

But to me, what I think is actually going on here is...

I think that functionality of movement throughout the whole body to facilitate

to facilitate the kind of skills that they have is training things that are getting left out when you just make sure that your heart and lungs are able to support your running or your cycling.

And I think that some of those involve

Are probably related.

I don't know what they're not dying of so presumably they're getting less heart disease or like getting less cancer And they're getting less neurological disease because that's what people are dying of right like that in the average If you get a far enough for someone to analyze why you died You know they're like diabetes and hip fractures and things like that are hitting younger people But in general if people are dying because they got old they're dying of heart disease first cancer second and they're a lot like they outlive those two things and

You get this diverse spread of things that people die of, and diverse neurological diseases becomes pretty heavy.

So I think cardiorespiratory fitness is probably the biggest thing in preventing heart disease.

But cancer becomes very interesting because there was a study in rodents that showed that stretching prevents tumor growth.

And I thought this was wild.

I first heard about this on one of Huberman's shows.

And so I looked up the study and I was like, this is wild because I happen to know some other things about immune function.

So one thing is that when T cells, which are important both to prevent infections and are also important because they attack you during autoimmunity, and they're also important because they kill cancer.

For T cells to be activated, what they do is they don't have enough energy themselves.

So they push off the local environment.

And that pushing off creates motor proteins inside that generate the energy to activate the T cell.

And what cancers do is they modify their extracellular environment to compromise that because it's harder for the T cell to push off of it.

Now I know another thing from Crohn's research, which is that the best way to cure Crohn's disease besides some of the drugs that they're on is a liquid diet.