Dan Bessison

But it has clear health benefits and has become a benchmark of what a clinically significant weight loss is. A little bit of weight loss helps.

But it has clear health benefits and has become a benchmark of what a clinically significant weight loss is. A little bit of weight loss helps.

Most lifestyle studies show that most people regain much of the weight. It's not like everybody regains all of the weight, but much of the weight is regained. What has happened over the last 25 years is a real explosion in our understanding of the biology that underlies weight regulation.

Most lifestyle studies show that most people regain much of the weight. It's not like everybody regains all of the weight, but much of the weight is regained. What has happened over the last 25 years is a real explosion in our understanding of the biology that underlies weight regulation.

Most lifestyle studies show that most people regain much of the weight. It's not like everybody regains all of the weight, but much of the weight is regained. What has happened over the last 25 years is a real explosion in our understanding of the biology that underlies weight regulation.

I think now we think of weight much like we think about blood pressure or glucose, that there's complex biology that the body's got its own idea about what it wants to weigh. And what it seems like the body wants to do, it doesn't regulate around a set point. It regulates around a trajectory of gradual weight gain across the life.

I think now we think of weight much like we think about blood pressure or glucose, that there's complex biology that the body's got its own idea about what it wants to weigh. And what it seems like the body wants to do, it doesn't regulate around a set point. It regulates around a trajectory of gradual weight gain across the life.

I think now we think of weight much like we think about blood pressure or glucose, that there's complex biology that the body's got its own idea about what it wants to weigh. And what it seems like the body wants to do, it doesn't regulate around a set point. It regulates around a trajectory of gradual weight gain across the life.

So the biology of weight really pushes back against efforts to change our diet. And so that's why people regain the weight is when they lose weight, the body goes, this is not good. And the people become more hungry, their energy expenditure goes down, and these things tend to push the weight back up to where it was before.

So the biology of weight really pushes back against efforts to change our diet. And so that's why people regain the weight is when they lose weight, the body goes, this is not good. And the people become more hungry, their energy expenditure goes down, and these things tend to push the weight back up to where it was before.

So the biology of weight really pushes back against efforts to change our diet. And so that's why people regain the weight is when they lose weight, the body goes, this is not good. And the people become more hungry, their energy expenditure goes down, and these things tend to push the weight back up to where it was before.

Only maybe 1% or 2% of people ever had that conversation, ever got that medication. And there are a number of reasons for that. One is the older medicines had some side effects. There were some bad stories about health problems with fen-phen and other medicines.

Only maybe 1% or 2% of people ever had that conversation, ever got that medication. And there are a number of reasons for that. One is the older medicines had some side effects. There were some bad stories about health problems with fen-phen and other medicines.

Only maybe 1% or 2% of people ever had that conversation, ever got that medication. And there are a number of reasons for that. One is the older medicines had some side effects. There were some bad stories about health problems with fen-phen and other medicines.

And I think two doctors and patients Doctors especially have this idea that, well, Mrs. Jones, you ought to be able to handle this on your own. This idea that weight is regulated, it's taken a long time to get any traction there. Doctors would say things like, you know, if you show me you can stick to a diet, well, then I'll maybe talk to you about a medicine.

And I think two doctors and patients Doctors especially have this idea that, well, Mrs. Jones, you ought to be able to handle this on your own. This idea that weight is regulated, it's taken a long time to get any traction there. Doctors would say things like, you know, if you show me you can stick to a diet, well, then I'll maybe talk to you about a medicine.

And I think two doctors and patients Doctors especially have this idea that, well, Mrs. Jones, you ought to be able to handle this on your own. This idea that weight is regulated, it's taken a long time to get any traction there. Doctors would say things like, you know, if you show me you can stick to a diet, well, then I'll maybe talk to you about a medicine.

We don't do that with diabetes or high blood pressure. We're very quick to go to a medication in those conditions. So I think there's a lot of maybe bias and stigma directed at people living with obesity that we tend to blame them for their health problem. So medicines that weren't super effective and an environment that really thought that people could do this on their own.

We don't do that with diabetes or high blood pressure. We're very quick to go to a medication in those conditions. So I think there's a lot of maybe bias and stigma directed at people living with obesity that we tend to blame them for their health problem. So medicines that weren't super effective and an environment that really thought that people could do this on their own.

We don't do that with diabetes or high blood pressure. We're very quick to go to a medication in those conditions. So I think there's a lot of maybe bias and stigma directed at people living with obesity that we tend to blame them for their health problem. So medicines that weren't super effective and an environment that really thought that people could do this on their own.