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David Allison

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
1010 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

That's the idea of nutrition.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

We may have to accept there are these limitations of our knowledge.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

So, for example, if you do a study of cheddar cheese made in Wisconsin,

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

and versus some appropriate control, and you say, look, this is what the effects I get of this, and so therefore cheese consumption has this effect.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

I said, well, Peter, are you sure it's cheese consumption in general, or is it just cheddar cheese?

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Is it just cheddar cheese made in Wisconsin?

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Or is it any cheddar cheese?

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Is it only cheddar cheese when eaten with these other things or these?

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

And I think that's something that's so hard to control in nutrition that we'll wind up with these statements of saying, it looks like it's cheddar cheese in general, and maybe we can do some other studies to suss it out, or it looks like it's cheese in general.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

But we'll always have this sort of saying, this looks like what it is.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Here's a good recommendation, but it's not absolute knowledge.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Yeah, I think it's important to distinguish between concave downward or a curve that doesn't keep accelerating, a decelerating curve, curve with a negative second derivative.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

versus non-monotonic.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

Those can be non-monotonic, but it's not the same thing.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

So one is the diminishing returns.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

It keeps going up, but it goes up ever more slowly.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

And there may be a point at which it never reaches.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

And that point that it never reaches may not be 100% of whatever it is you're thinking about.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

That's different than saying an LCA actually goes down at some point.

The Peter Attia Drive
#368 โ€’ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

So a lot of things go down at some point, right?