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David Feldman

👤 Person
702 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

And therefore, a lot of people who are low-carb who even had high LDL cholesterol were saying, well, but I have pattern A, so I don't think I'm that much at risk. But even then, there was still a lot of debate. There, yes, were a number of people were saying, I just don't even care that much as long as I'm pattern A. I don't care how high my cholesterol goes.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

And therefore, a lot of people who are low-carb who even had high LDL cholesterol were saying, well, but I have pattern A, so I don't think I'm that much at risk. But even then, there was still a lot of debate. There, yes, were a number of people were saying, I just don't even care that much as long as I'm pattern A. I don't care how high my cholesterol goes.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

There were definitely a lot of people who were saying, well, you know, I could be more okay with my LDL being, say, 180 or 190 i have a problem with it getting up there to say 300 400 500 And that was a new phenomenon. Even within the low-carb community, that was actually pretty new.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

There were definitely a lot of people who were saying, well, you know, I could be more okay with my LDL being, say, 180 or 190 i have a problem with it getting up there to say 300 400 500 And that was a new phenomenon. Even within the low-carb community, that was actually pretty new.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

There were definitely a lot of people who were saying, well, you know, I could be more okay with my LDL being, say, 180 or 190 i have a problem with it getting up there to say 300 400 500 And that was a new phenomenon. Even within the low-carb community, that was actually pretty new.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

I'm going to do my best to give a very brief overview of what I would call the lipid energy model, which we've now established and published with the enormous help of your prior guest, Nick Norwitz and Adrian Sotomoda. The three of us have actually codified a lot of this into the literature, but this is kind of how it works.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

I'm going to do my best to give a very brief overview of what I would call the lipid energy model, which we've now established and published with the enormous help of your prior guest, Nick Norwitz and Adrian Sotomoda. The three of us have actually codified a lot of this into the literature, but this is kind of how it works.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

I'm going to do my best to give a very brief overview of what I would call the lipid energy model, which we've now established and published with the enormous help of your prior guest, Nick Norwitz and Adrian Sotomoda. The three of us have actually codified a lot of this into the literature, but this is kind of how it works.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

We're constantly talking about metabolic health, but what is metabolic health? What actually establishes it? Well, metabolism is that balance, right, between anabolism and catabolism. You're breaking down and building up. But what we're usually talking about is fuel.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

We're constantly talking about metabolic health, but what is metabolic health? What actually establishes it? Well, metabolism is that balance, right, between anabolism and catabolism. You're breaking down and building up. But what we're usually talking about is fuel.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

We're constantly talking about metabolic health, but what is metabolic health? What actually establishes it? Well, metabolism is that balance, right, between anabolism and catabolism. You're breaking down and building up. But what we're usually talking about is fuel.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So when you're consuming particularly something like carbohydrates, you're storing your fuel as stored glucose, which is in the form of glycogen. That's fine, but that's a small container within your body, whereas fat, we have a fairly large container with regard to our adipose tissue.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So when you're consuming particularly something like carbohydrates, you're storing your fuel as stored glucose, which is in the form of glycogen. That's fine, but that's a small container within your body, whereas fat, we have a fairly large container with regard to our adipose tissue.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So when you're consuming particularly something like carbohydrates, you're storing your fuel as stored glucose, which is in the form of glycogen. That's fine, but that's a small container within your body, whereas fat, we have a fairly large container with regard to our adipose tissue.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So if you've got good metabolic health, if you're good at pulling the fuel out and putting it back away again, but you're powered more by fat, What's relevant, that fat in the blood needs a carrier. And the biggest bulk carrier are these complexes called lipoproteins. So that LDL I mentioned earlier, that's short for low-density lipoprotein.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So if you've got good metabolic health, if you're good at pulling the fuel out and putting it back away again, but you're powered more by fat, What's relevant, that fat in the blood needs a carrier. And the biggest bulk carrier are these complexes called lipoproteins. So that LDL I mentioned earlier, that's short for low-density lipoprotein.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So if you've got good metabolic health, if you're good at pulling the fuel out and putting it back away again, but you're powered more by fat, What's relevant, that fat in the blood needs a carrier. And the biggest bulk carrier are these complexes called lipoproteins. So that LDL I mentioned earlier, that's short for low-density lipoprotein.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So these lipoproteins, if you're trafficking them more in the body, particularly if you have to move more of those fatty acids around, it gets a bit complex. But we would argue that cholesterol is ride-sharing in that process, in these containers. That's the reason why you're seeing higher LDL cholesterol.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So these lipoproteins, if you're trafficking them more in the body, particularly if you have to move more of those fatty acids around, it gets a bit complex. But we would argue that cholesterol is ride-sharing in that process, in these containers. That's the reason why you're seeing higher LDL cholesterol.

Dhru Purohit Show
Is Current Thinking Around Cholesterol Outdated? What You Need to Know About Heart Health and The Root Cause of Plaque Build Up with David Feldman

So these lipoproteins, if you're trafficking them more in the body, particularly if you have to move more of those fatty acids around, it gets a bit complex. But we would argue that cholesterol is ride-sharing in that process, in these containers. That's the reason why you're seeing higher LDL cholesterol.