Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

David Maher

👤 Speaker
77 total appearances

Appearances Over Time

Podcast Appearances

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

And that can have a small impact on the effectiveness of the vaccine.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

And you know, every so often we get a season where you might get this mismatch and it makes the vaccine not as effective as it should be.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

That issue is completely removed with the use of the mammalian cells because they're a better match to us as people.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

When we grow these cells in the laboratory, we just want a very safe cell line that can be used over and over again.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

And this cell line, which was produced years ago, like you said, it's just a very convenient, easy way to grow the cells in the laboratory rather than using human cells.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

We built this new facility out at Tullamarine.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

It's replacing the facility we had here in Melbourne that used the egg based technology.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

It's capable of producing 150 million doses of pandemic vaccine within the first wave of the pandemic, which is around about sort of four to six months time.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

So we target to have at least two doses for every Australian in those initial months of a pandemic.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

We had the same sort of timeframes for the egg-based vaccines.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

With the new technology, I think it just adds an enormous amount of robustness, better matches, supply chain security control, and we can store all of the raw materials.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

It can be sitting there as a stockpile for us, ready to go, rather than needing a risky supply chain with chickens.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

It is.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

I actually got my Fluad shot yesterday, which is giving away my age a bit.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

Yeah, so we still make that in eggs.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

So eggs are still a very good method for making the flu vaccine in terms of its effectiveness.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

We are looking eventually to shift to a cell-based vaccine for the elderly, but that's still a couple of years away.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

Yeah, it's to do with the growth characteristics of the individual strains.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

Some strains grow better in eggs and in cell.

The Science Show
Celebrating David Attenborough’s 100th birthday and a new way of making vaccines

And so the WHO, the World Health Organization, does all of the surveillance globally and chooses the strains for the individual seasons.