Dennis McKenna
๐ค SpeakerAppearances Over Time
Podcast Appearances
So you get tryptophan, you remove the carboxyl group, you get tryptamine. You stick two methyl groups on that, another enzyme comes along called N-methyltransferase, I love biochemistry because the name of enzymes describe what they do, right? And methyltransferase, it sticks methyl groups on things, CH3 groups on things. So two steps from tryptophan, you get DMT.
And then from that, you get all these variations, bufotenine, fibethoxy DMT, psilocybin. You get this whole tryptamine family of most of which are psychoactive. But DMT is the primary hallucinogenic or psychedelic tryptamine, and it's the simplest one. It's not orally active. And actually, you could eat plants that contain DMT and people do. It's the part of some people's diet.
And then from that, you get all these variations, bufotenine, fibethoxy DMT, psilocybin. You get this whole tryptamine family of most of which are psychoactive. But DMT is the primary hallucinogenic or psychedelic tryptamine, and it's the simplest one. It's not orally active. And actually, you could eat plants that contain DMT and people do. It's the part of some people's diet.
And then from that, you get all these variations, bufotenine, fibethoxy DMT, psilocybin. You get this whole tryptamine family of most of which are psychoactive. But DMT is the primary hallucinogenic or psychedelic tryptamine, and it's the simplest one. It's not orally active. And actually, you could eat plants that contain DMT and people do. It's the part of some people's diet.
But because they're not taking MAO inhibitors, they never suspect they're taking a hallucinogen. For example, DMT occurs in oranges. And lemons and things like that at low levels, you know, but it's there. DMT, I think there are thousands of plants that contain DMT. It's not rare at all. Not all plants express DMT in great quantities, but it's there.
But because they're not taking MAO inhibitors, they never suspect they're taking a hallucinogen. For example, DMT occurs in oranges. And lemons and things like that at low levels, you know, but it's there. DMT, I think there are thousands of plants that contain DMT. It's not rare at all. Not all plants express DMT in great quantities, but it's there.
But because they're not taking MAO inhibitors, they never suspect they're taking a hallucinogen. For example, DMT occurs in oranges. And lemons and things like that at low levels, you know, but it's there. DMT, I think there are thousands of plants that contain DMT. It's not rare at all. Not all plants express DMT in great quantities, but it's there.
And then some do actually produce significant amounts of it, like acacias, for example. Acacia, which is primarily โ I mean acacia is about 1,200 genera or 1,200 species all through Africa, mostly Australia concentrated. Some of the most potent sources of DMT and other tryptamines are found in acacias, which ironically happens to be โ they're known as โ generically they're known as wattles.
And then some do actually produce significant amounts of it, like acacias, for example. Acacia, which is primarily โ I mean acacia is about 1,200 genera or 1,200 species all through Africa, mostly Australia concentrated. Some of the most potent sources of DMT and other tryptamines are found in acacias, which ironically happens to be โ they're known as โ generically they're known as wattles.
And then some do actually produce significant amounts of it, like acacias, for example. Acacia, which is primarily โ I mean acacia is about 1,200 genera or 1,200 species all through Africa, mostly Australia concentrated. Some of the most potent sources of DMT and other tryptamines are found in acacias, which ironically happens to be โ they're known as โ generically they're known as wattles.
In Australia, the wattle is the national tree of Australia. There's no record that Aborigines use these things, but they have been there. My theory is that there's probably trace amounts of DMT in all plants because of these enzymes. Decarboxylases and methyltransferases are pretty much involved in cellular processes at all levels. Nobody's going to do this and nobody's going to fund it.
In Australia, the wattle is the national tree of Australia. There's no record that Aborigines use these things, but they have been there. My theory is that there's probably trace amounts of DMT in all plants because of these enzymes. Decarboxylases and methyltransferases are pretty much involved in cellular processes at all levels. Nobody's going to do this and nobody's going to fund it.
In Australia, the wattle is the national tree of Australia. There's no record that Aborigines use these things, but they have been there. My theory is that there's probably trace amounts of DMT in all plants because of these enzymes. Decarboxylases and methyltransferases are pretty much involved in cellular processes at all levels. Nobody's going to do this and nobody's going to fund it.
But I'll bet if you went out and just started picking plants at random and analyzing them for DMT, you would find trace amounts of DMT and in some cases large amounts. And those are the ones that have become utilized like the chacruna.
But I'll bet if you went out and just started picking plants at random and analyzing them for DMT, you would find trace amounts of DMT and in some cases large amounts. And those are the ones that have become utilized like the chacruna.
But I'll bet if you went out and just started picking plants at random and analyzing them for DMT, you would find trace amounts of DMT and in some cases large amounts. And those are the ones that have become utilized like the chacruna.
psychotria, which is the admixture plant for ayahuasca, or these anagenanthra snuffs that are the seeds are made into stuff, or the ukuhe that we were talking about, the varolas. They contain large amounts of DMT. And indigenous people have, you know, they're very clever.
psychotria, which is the admixture plant for ayahuasca, or these anagenanthra snuffs that are the seeds are made into stuff, or the ukuhe that we were talking about, the varolas. They contain large amounts of DMT. And indigenous people have, you know, they're very clever.
psychotria, which is the admixture plant for ayahuasca, or these anagenanthra snuffs that are the seeds are made into stuff, or the ukuhe that we were talking about, the varolas. They contain large amounts of DMT. And indigenous people have, you know, they're very clever.
They want to get high just like everybody does, but they become very clever at identifying these plants and learning how to prepare them.