Derek (More Plates More Dates)

You know, that's like the kind of like disparity in these communities.

And they all have like some it's it's not like they're both wrong.

Like everyone has their own individual drug response.

And some people have like the most insane response to Tylenol.

You know, it's not like anything is risk free in this world.

So just be aware that these are ultimately hormone therapies that you're getting on.

Like it's not, it will also not dramatically, but could suppress fertility metrics mildly because intratesticular androgenic signaling does dictate spermatogenesis.

That includes DHT.

So like if you're reducing the DHT a lot, that might impede your fertility to some extent too, even if you're natural and have no, you know, testosterone therapy and you're like a eugenital male.

But yeah, the most impactful therapy for sure intervention wise is going to be inhibiting DHT.

The degree to which you inhibit it will be dictated on how susceptible you are.

But if you nuke DHC into nothingness via high dose Dutasteride, it's pretty difficult, if not near impossible to lose hair as a male.

Now.

The most susceptible might need to be on a topical antiandrogen or maybe their side effect profile would be superior with a lower DHT inhibition and some sort of adjunct topical antiandrogen therapy with it or some topical 5-alpha reductase inhibition with the topical antiandrogen.

It's all kind of like a...

a bit of a strategy approach based on your individual risk profile and what you want to take.

But if you don't attenuate miniaturization potential, like you're not going to prevent hair loss.

You could take minoxidil all day.

You could take all the pumpkin seed oil, saw palmetto, dump sulfur on your head, do whatever you want.

Like it's not going to move the needle for inhibiting miniaturization mediated through androgens, which is ultimately what it is.