Derek Thompson
đ€ SpeakerAppearances Over Time
Podcast Appearances
So let's talk about your discovery. And I want to build up to last month's breakthrough slowly. Your lab studies rare survivors of pancreatic cancer. It studies them to understand how these survivors' immune systems are different. What have you found?
So let's talk about your discovery. And I want to build up to last month's breakthrough slowly. Your lab studies rare survivors of pancreatic cancer. It studies them to understand how these survivors' immune systems are different. What have you found?
So you find these group of super survivors and your goal is to replicate their immune system response for other patients. Why did you try to do this through RNA vaccines?
So you find these group of super survivors and your goal is to replicate their immune system response for other patients. Why did you try to do this through RNA vaccines?
So you find these group of super survivors and your goal is to replicate their immune system response for other patients. Why did you try to do this through RNA vaccines?
All right, you build these RNA vaccines with your colleagues in biopharma. You conduct your first cancer vaccine clinical trial. Tell us what you did. Tell us what you found.
All right, you build these RNA vaccines with your colleagues in biopharma. You conduct your first cancer vaccine clinical trial. Tell us what you did. Tell us what you found.
All right, you build these RNA vaccines with your colleagues in biopharma. You conduct your first cancer vaccine clinical trial. Tell us what you did. Tell us what you found.
So at the highest level, it seems like you've proved that a cancer vaccine, a personalized cancer vaccine, can teach certain patients' immune systems to recognize a previously unrecognizable cancer. That sounds exciting to me. What's most exciting about this result to you?
So at the highest level, it seems like you've proved that a cancer vaccine, a personalized cancer vaccine, can teach certain patients' immune systems to recognize a previously unrecognizable cancer. That sounds exciting to me. What's most exciting about this result to you?
So at the highest level, it seems like you've proved that a cancer vaccine, a personalized cancer vaccine, can teach certain patients' immune systems to recognize a previously unrecognizable cancer. That sounds exciting to me. What's most exciting about this result to you?
All this good news, and we still haven't covered the breakthrough that you reported in Nature last month. What did you discover in the last two years that demanded yet another positive update on these cancer vaccines?
All this good news, and we still haven't covered the breakthrough that you reported in Nature last month. What did you discover in the last two years that demanded yet another positive update on these cancer vaccines?
All this good news, and we still haven't covered the breakthrough that you reported in Nature last month. What did you discover in the last two years that demanded yet another positive update on these cancer vaccines?
So people are familiar with RNA vaccines for COVID. How is this class of therapies that you're developing similar or different to the mRNA therapies that we know from Pfizer and Moderna?
So people are familiar with RNA vaccines for COVID. How is this class of therapies that you're developing similar or different to the mRNA therapies that we know from Pfizer and Moderna?
So people are familiar with RNA vaccines for COVID. How is this class of therapies that you're developing similar or different to the mRNA therapies that we know from Pfizer and Moderna?
It's a fabulous answer. And it raises a question that with the COVID vaccines, we could scale them immensely with the understanding that you got the same COVID vaccine that I got, that my wife got, that my friend got. All the same shot, and it could be batched in one place and just mass manufactured. You cannot do that, by definition, with a personalized cancer vaccine.
It's a fabulous answer. And it raises a question that with the COVID vaccines, we could scale them immensely with the understanding that you got the same COVID vaccine that I got, that my wife got, that my friend got. All the same shot, and it could be batched in one place and just mass manufactured. You cannot do that, by definition, with a personalized cancer vaccine.
It's a fabulous answer. And it raises a question that with the COVID vaccines, we could scale them immensely with the understanding that you got the same COVID vaccine that I got, that my wife got, that my friend got. All the same shot, and it could be batched in one place and just mass manufactured. You cannot do that, by definition, with a personalized cancer vaccine.