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Dr. Abraham Morgentaler

๐Ÿ‘ค Speaker
944 total appearances

Appearances Over Time

Podcast Appearances

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

at the end of one year after they started, is only 15%, one out of seven. People stop it. So a lot of urologists I know say, oh no, my patients stay on it. But unless you actually look at your numbers, There's a lot of bias involved with that because we know that we see the patients that come back to us. We don't see the patients that don't come back to us. And we may not remember them.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

at the end of one year after they started, is only 15%, one out of seven. People stop it. So a lot of urologists I know say, oh no, my patients stay on it. But unless you actually look at your numbers, There's a lot of bias involved with that because we know that we see the patients that come back to us. We don't see the patients that don't come back to us. And we may not remember them.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

at the end of one year after they started, is only 15%, one out of seven. People stop it. So a lot of urologists I know say, oh no, my patients stay on it. But unless you actually look at your numbers, There's a lot of bias involved with that because we know that we see the patients that come back to us. We don't see the patients that don't come back to us. And we may not remember them.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

We see them once, maybe twice, and off they go to learn how to do self-injections. So unless you're keeping statistics on your own, folks, it's hard to know. So injections are fine. It's a good form of therapy. We would give patients the choice of doing self-injection which they could do once a week, usual starting dose is 100 milligrams or half a cc.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

We see them once, maybe twice, and off they go to learn how to do self-injections. So unless you're keeping statistics on your own, folks, it's hard to know. So injections are fine. It's a good form of therapy. We would give patients the choice of doing self-injection which they could do once a week, usual starting dose is 100 milligrams or half a cc.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

We see them once, maybe twice, and off they go to learn how to do self-injections. So unless you're keeping statistics on your own, folks, it's hard to know. So injections are fine. It's a good form of therapy. We would give patients the choice of doing self-injection which they could do once a week, usual starting dose is 100 milligrams or half a cc.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Or if they didn't want to do it, we would inject them in the office. They'd come in every two weeks. Once a week is too much for, you know, a lot of people have to take time off from work and fight traffic in a city like Boston and Park and all that. So we'd have them come in every two weeks and we would inject them starting dose 200 milligrams or one cc. And we can adjust the dose after that.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Or if they didn't want to do it, we would inject them in the office. They'd come in every two weeks. Once a week is too much for, you know, a lot of people have to take time off from work and fight traffic in a city like Boston and Park and all that. So we'd have them come in every two weeks and we would inject them starting dose 200 milligrams or one cc. And we can adjust the dose after that.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

Or if they didn't want to do it, we would inject them in the office. They'd come in every two weeks. Once a week is too much for, you know, a lot of people have to take time off from work and fight traffic in a city like Boston and Park and all that. So we'd have them come in every two weeks and we would inject them starting dose 200 milligrams or one cc. And we can adjust the dose after that.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

The gels, people say, oh, the gels, the topicals, what a nuisance that is. But there were about, I don't know, 10 plus years where the leading testosterone product in the United States, at least, were the gels. And they have advantages that it's not an injection. There's nothing scary about it. Patient has some control over doing it. They just apply it themselves.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

The gels, people say, oh, the gels, the topicals, what a nuisance that is. But there were about, I don't know, 10 plus years where the leading testosterone product in the United States, at least, were the gels. And they have advantages that it's not an injection. There's nothing scary about it. Patient has some control over doing it. They just apply it themselves.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

The gels, people say, oh, the gels, the topicals, what a nuisance that is. But there were about, I don't know, 10 plus years where the leading testosterone product in the United States, at least, were the gels. And they have advantages that it's not an injection. There's nothing scary about it. Patient has some control over doing it. They just apply it themselves.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

They feel like they have control too. Like, you know, there's nothing really bad that happens with testosterone therapy, but you have the sense if you're applying a cream or a gel every day that you can stop it. You know, if you're worried something's happening, then you just stop doing it, whereas the injection, it's in there.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

They feel like they have control too. Like, you know, there's nothing really bad that happens with testosterone therapy, but you have the sense if you're applying a cream or a gel every day that you can stop it. You know, if you're worried something's happening, then you just stop doing it, whereas the injection, it's in there.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

They feel like they have control too. Like, you know, there's nothing really bad that happens with testosterone therapy, but you have the sense if you're applying a cream or a gel every day that you can stop it. You know, if you're worried something's happening, then you just stop doing it, whereas the injection, it's in there.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So, you know, the longer acting treatments, pellets, and the longer acting testosterone injections, testosterone and decanoate, you know, they have advantages, which is that the treatment is less frequent. But there are issues around insurance or cost and, you know, there's a lot that goes into what actually will work for somebody.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So, you know, the longer acting treatments, pellets, and the longer acting testosterone injections, testosterone and decanoate, you know, they have advantages, which is that the treatment is less frequent. But there are issues around insurance or cost and, you know, there's a lot that goes into what actually will work for somebody.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

So, you know, the longer acting treatments, pellets, and the longer acting testosterone injections, testosterone and decanoate, you know, they have advantages, which is that the treatment is less frequent. But there are issues around insurance or cost and, you know, there's a lot that goes into what actually will work for somebody.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

No, I think the data are quite clear that it does not cause blood clots. You know, we just had published over the last year or so the TRAVERSE trial. So TRAVERSE was the largest randomized control trial ever with testosterone. It involved more than 5,000 men randomized either to testosterone gel or placebo gel. Mean follow-up was 33 months, so a little bit less than three years.

BackTable Urology
Ep. 188 Testosterone Therapy Today: Clinical Advances and Safety with Dr. Abraham Morgentaler

No, I think the data are quite clear that it does not cause blood clots. You know, we just had published over the last year or so the TRAVERSE trial. So TRAVERSE was the largest randomized control trial ever with testosterone. It involved more than 5,000 men randomized either to testosterone gel or placebo gel. Mean follow-up was 33 months, so a little bit less than three years.