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Dr. Abud Bakri

๐Ÿ‘ค Speaker
1676 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Or it could be that it's modifying certain proteins that already exist or linking different proteins together in a more favorable fashion for gene transcription.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

The Russian peptides are all epigenetic modifiers that they bind to the groove of the DNA in certain spots that either open up or close the chromatin to certain areas of genetic expression.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And they've modeled this out.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Like a steroid hormone.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So steroid hormones bind, like they bind to a, like the end receptor binds DHT or testosterone, goes into the nucleus, turns on all the androgenic genes.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Yeah.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Like puberty is a good example of that.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Yes, exactly.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Exactly.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So like penelion that we've talked about, uh, shuttles, uh, heat shock proteins with androgen receptors.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Got it.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

best way to look at it is you know as humans we've been looking for medicines in plants for thousands of years and in the last let's say 150 years we've been looking for medicines in cells so animal derived versus plant plant derived medicines is the way you think about it you think about aspirin you think about metformin the statins those were all discovered in you know plant tissues um statins more so fungi but you get the point now we've been looking into animal tissues to find cures medicines treatments

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So a group in Croatia in the 90s looks out for this peptide called BPC, eventually named BPC.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

It's a 40,000 Dalton giant peptide called BPC.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

BPC-157 is 15 amino acids from that giant peptide.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

We don't naturally make BPC-157.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

That's what you'll commonly hear online.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

We make BPC the big peptide.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

protein.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

what eventually became BPC.