Dr. Abud Bakri

So I will see some calcification on MRIs when we have a patient come in for like a stroke or a TBI, we'll look at their MRI.

I'm like, hey, that looks like a little bit of calcification there.

Maybe my neurology colleagues will disagree, but that seems to happen.

But the question is, what is actually leading to the deterioration of melatonin synthesis?

Because it decreases quite dramatically.

And some people even think that might start puberty.

Like if you have a pineal cyst,

you can have precocious puberty like at eight or nine years old.

Yep.

So in Kevin's work, he's found that it will increase the expression of the different clock genes.

So in like, you know, lymphocytes that he'll measure in peripheral tissues, he'll notice that the clock genes actually change.

So in a more rhythmic pattern, he'll notice that morning cortisol is higher.

Great.

And cognitive function.

I mean, I've had 28-hour shifts, and that's what got me interested in security.

You're young.

You're good.

But yeah, the idea was restoring a more—

a circadian appropriate hormonal profile through, you know, ACTH, cortisol.

Take and when?