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Dr. Abud Bakri

πŸ‘€ Speaker
1676 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

It's a gland that both secretes hormones and develops the T cells.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So your lymphatic cells are found in your bone marrow.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

That's where they're made.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

the T cells will travel up to the thymus and get trained so they don't kill you and they don't attack your own tissue, but attack a foreign invader or a cancer or whatever it may be.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

That process is very good in youth.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And as you age, you get more autoimmunity, more cancers, et cetera, et cetera, because the immune system is not as robust, both because the thymus makes less of the hormones that train the immune cells and makes less of these immune cells themselves.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So when you're, you know, 15, you're making, uh,

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

10 to the eighth magnitude of these cells every single day.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They're called naive T cells.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They will eventually become your CD4 and CD8 T cells.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

As you age, this number dramatically decreases.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And those cells will live somewhere between 10 and 15 years.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And that can kind of

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

gauge when the mortality window kicks in for a lot of these different disorders.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

When your thymus reaches a minimum level of output, you get a lot of these disorders like cancers, heart disease, autoimmunity.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

If you put almost any disease and look at the thymus risk associated with it, it increases as the thymus function

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

There's a Nature paper, 2026, just came out that looked at cardiovascular disease and cancer mortality and all these different metrics that they did MRIs of people.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And the people that had the higher thymic scores had less mortality across every single one of these conditions.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

But you said...

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

It's just a few cells and yet it's somehow maintaining function.