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Dr. Abud Bakri

๐Ÿ‘ค Speaker
1676 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

And then they were like, what's causing the actual biological effects?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They identified BPC-157, the 15-amino acid peptide that's causing all these effects.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

There's actually more peptides in gastric juices that some other scientists may or may not have already identified.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

This field of peptides is going to be very interesting because almost every organ has a signature of peptides.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Like if you think back, Dr. Vladimir Vulevich in 1850s, 1880s, finds carnosine and carnitine in muscle of cattle.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So you can think about the first peptides that are found are carnosine and then carnitine is the amino acid that have positive effects on strength training and performance and different

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

effects there.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

But that was the whole idea is like, hey, there's muscle peptides that may have muscle effects, right?

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Gut peptides may have gut effects.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Yep.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So they did all kinds of horrible things to these mice.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They would sever tendons and then give them BPC through oral or injectable intraperitoneal administrations, and they'd have faster healing times.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They would sever ACLs of the mice.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They would do burn wounds.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

So when a patient has a burn wound in the ICU, they end up having crazy gastric ulcers.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

But if they were able to put BPC on topically for the mouse, they would have no gastric ulcers.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

They name it as this anti-stress compound.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

It's how they look at it.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

Now, when they do that Achilles paper on the mice, that's what explodes the bodybuilder interest and leads us to today where we are like, oh, MSK injuries must be BPC, tendons and muscle injuries.

Huberman Lab
Peptides: The Science, Uses & Safety | Dr. Abud Bakri

But the original idea of BPC was to use it as a gastric treatment, not to use it as a musculoskeletal.