Dr. Abud Bakri
π€ SpeakerAppearances Over Time
Podcast Appearances
Now, is that significant?
That seems to be significant.
But no one's really kind of discussing it, unfortunately.
Yeah.
So when it comes to, let's parse out the effects and the different types of compounds that exist in this category.
So there's the ghrelin side, the ghrelin agonist, like MK-677, not FDA approved, orally available pill that makes you bleed out growth hormone.
Like you make so much growth hormone in response to that.
And in non-pulsatile fashion, growth hormone is a very circadian hormone that gets released in the first 90 minutes of slow wave sleep.
And if you miss that big pulse, you're going to get small pulses throughout the day.
The question is, is that big pulse better than small little, you know, mini pulses throughout the day?
These secretagogues will address the broader category of something called somatopause.
So you've heard of menopause.
You've heard of maybe andropause.
Somatopause is this event that happens somewhere in the 30s where growth hormone production dramatically decreases.
So if we kind of paint a picture, your pineal gland's aging.
before puberty, your thymus right after puberty, you know, in your 20s.
And in your 30s, you're having somatopause.
That's where your growth hormone production is decreasing.
You're having, they call it adrenopause, where your adrenals stop making as much DHEA and the different ratio of cortisol.
And then you're having menopause, andropause, and all the other chronic conditions.