Dr. Abud Bakri

So if you like peruse Reddit, which you should never do, you'll find all these anhedonia discussions about BPC.

People feel like depressed and low energy.

Incredible.

So it seems to be homeostatic.

In the literature, when it comes to the animal data, they've injected animals with 1,000 times the dose of BPC with no real adverse effects.

So we don't even know the LD50 of BPC, which makes it hard for it to become an FDA-approved.

Maybe define LD50.

LD50 is the dose of which would kill 50% of the animals if it was administered to them.

So we don't even know what that is.

To be a clinician to prescribe this, we need to know what that is, which limits us.

Now, there was two very small phase one and phase two trials on rectal BPC enemas in the early 2000s from that same Croatian group.

So that's the big concern of BPC.

All the data comes from one group, so people can be skeptical.

There's a couple of Chinese groups that have also replicated some of their work.

But those groups wanted to try to treat ulcerative colitis.

It's a very miserable condition of where the immune system attacks the lining of the gut in multiple spots.

And they use enemas of BPC up to like 80 milligrams, which is much more than people would take.

Most people are injecting microgram.

Yes.

100 or 200 micrograms per day or something.