Dr. Alok Kanojia (Dr. K)
speaker
1,658 appearances
5 recordings
3 series
first heard Sep 2025
last heard 27 May
Dr. Alok Kanojia (Dr. K)’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 4 in all, peaking in Oct 2025 with 2.
Appearances
They have antidepressant effects.
anxiolytic effects, also reduce suicidality, and can alter things like alcohol usage and PTSD.
So now let's take a look at what the serotonin receptor actually does.
Psychedelics are serotonin 2A receptor agonists, including LSD, ayahuasca, DMT,
and psilocybin, also MDMA.
So the 2A receptor and specifically psychedelics also increase the functional connectivity of the brain.
So psychedelics are different from traditional antidepressants and anti-anxiety medications because they do a couple of other things.
So they have those mood reducing effects just like antidepressants.
But what we also know about psychedelics is that they increase neuroplasticity, which is the ability for our brain to rewire.
They increase neurogenesis, which is the ability of our brain to grow new neurons, like basically reproduce neurons.
That's mediated by something called brain-derived neurotrophic factor, which is something that stimulates neuronal growth.
And then they also increase the way that our brain or change the way that our brain talks to other parts of our brain.
So they change the connections between different parts of the brain.
So we see neurogenesis, we see neuroplasticity, and we see functional connectivity changes.
What psychedelics do is change our brain into edit mode.
So this is something that I want y'all to understand.
So when I work with people with psychedelics, I've seen two things, okay?
I've seen a lot of people will use psychedelics and in clinical settings and certain like shamans and things like that, they will have positive transformative experiences that lead to significant improvements in their mental health.
But I have also seen a ton of people who have used psychedelics and really screwed up their brains.
I've seen psychedelics not only be used to treat PTSD, but I've seen plenty of people who have used psychedelics and have traumatized themselves through bad trips.
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