Dr. Alok Kanojia (Dr. K)
speaker
1,658 appearances
5 recordings
3 series
first heard Sep 2025
last heard 27 May
Dr. Alok Kanojia (Dr. K)’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 4 in all, peaking in Oct 2025 with 2.
Appearances
And then we also have studies on things like alcoholism, where you'll notice that when we look at something like LSD for alcoholism,
And psilocybin for alcoholism, what we start to see is that these are a lot more crossing the midline, right?
So this doesn't seem to be as effective for substance use disorders as it is for something like treatment-resistant depression.
So the key thing here is here's LSD for alcoholism, and it crosses the midline, which means it's not very statistically significant.
Here's psilocybin for alcoholism.
This one crosses the midline.
These two don't.
So this appears like psilocybin is more effective for alcoholism than LSD is.
And then we can look at MDMA for PTSD.
So this is super exciting as well because we don't have great pharmacologic agents for PTSD, right?
We have to do a lot of physiologic rewiring.
We sort of walk you all through that process in Dr. K's Guide to Trauma.
If you all want to know like how to rewire your brain and identity and physiology, like we go through that process.
So this is what's really cool because we don't have like great drugs for PTSD, but MDMA seems quite promising, right?
We're seeing a lot of reductions that are not crossing the midline.
So it seems like psychedelics do have very promising efficacy for things like treatment resistant depression, PTSD, alcohol use disorder.
Not all psychedelics are the same.
And the key thing to remember is that the way in which we use them seems to be responsible for the benefits that we get.
OK, so if you're super depressed and traumatized and you're just get using psychedelics in your house at home, it's not clear to me that that is going to be safe or effective.
So now let's move on to safety.
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