Dr. Alok Kanojia (Dr. K)

You know, I've worked with people like this who will go for like one month and they'll be like in the Amazon rainforest guided by...

Like shamans who you have a very restricted diet, they'll give you ayahuasca.

Sometimes you'll take it every day for about 30 days.

Sometimes you'll eat very little and you have a lot of people who will sort of guide you through the process.

And in cases where your mindset is good, positive, you know, you're kind of focused, you're ready to do something and you have enough support structure, whether that's a shaman in a spiritual tradition or someone like a medical doctor, like a psychiatrist, those become really, really important for a sort of

creating the healing effects and protecting you from the negative effects.

And what I've seen is that there are a lot of people who think, oh, psychedelics can cure me of my PTSD, but they have no idea that the studies that show that are 14-week trials where therapists are sitting with you for eight hours during the trip, where someone is sort of there and sort of protecting you and keeping you safe.

And then what they'll do is they'll think, oh, I'm super depressed.

I need to feel better.

Let me take this high dose of LSD because they've heard about the heroic dose or psilocybin.

And what it'll actually do is induce a state of neuroplasticity where you have no guardrails.

You'll get even further traumatized.

The depression will get worse.

And then when your brain you'll edit your code in kind of a random way, right, because you're not controlling anything there.

And then when you hit control S, you end up more screwed up than before.

The main mechanism of action is that they induce neuroplasticity, but what happens when your brain is in the neuroplastic state becomes incredibly important.

So next, let's see which kind of psychedelics have what effects on which diseases, right?

So if you guys are like wondering, this is a great paper.

It's called...

efficacy and safety of psychedelics for the treatment of mental disorders, a systematic review and meta-analysis.