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Dr. Andy Galpin

๐Ÿ‘ค Speaker
9972 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

If both those individuals, let's say we had two people, one having issues with sleep, one not, both enrolled in the same study, you're going to see the magnitude of effect of the supplement or the nutritional factor gets a little bit washed out. So those are common themes you will see. I won't bring this up again, because honestly, I could do that with just about every single study.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

If both those individuals, let's say we had two people, one having issues with sleep, one not, both enrolled in the same study, you're going to see the magnitude of effect of the supplement or the nutritional factor gets a little bit washed out. So those are common themes you will see. I won't bring this up again, because honestly, I could do that with just about every single study.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

But it's something for you to really consider in the back of your mind. All right. Now, the goal then is to present to you information that I think has a strength of evidence, I'll explain to you what my criteria for a strong evidence is a little bit later. And things that I think kind of justify what we'll call low risk and high potential reward.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

But it's something for you to really consider in the back of your mind. All right. Now, the goal then is to present to you information that I think has a strength of evidence, I'll explain to you what my criteria for a strong evidence is a little bit later. And things that I think kind of justify what we'll call low risk and high potential reward.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And we'll typically break those down into things you can do before the injury. during or immediately after the injury, as well as long-term post-recovery. So you can think about that as pre, peri, or post, or simply preventative, and then treatments post-injury. So in terms of terminology, I'm gonna try to be consistent with three basic phrases.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And we'll typically break those down into things you can do before the injury. during or immediately after the injury, as well as long-term post-recovery. So you can think about that as pre, peri, or post, or simply preventative, and then treatments post-injury. So in terms of terminology, I'm gonna try to be consistent with three basic phrases.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So a brain injury is often broken up into three categories based on the severity. There's mild, which is the lowest, moderate, and severe. Now fortunately, mild is by far the most common. In fact, some papers indicate that over 90 plus percent of brain injuries are qualified as mild. What that means typically is there is a 30 minute or less change in state of consciousness.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So a brain injury is often broken up into three categories based on the severity. There's mild, which is the lowest, moderate, and severe. Now fortunately, mild is by far the most common. In fact, some papers indicate that over 90 plus percent of brain injuries are qualified as mild. What that means typically is there is a 30 minute or less change in state of consciousness.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So if you were unconscious for a couple of minutes, you probably had a mild traumatic brain injury. This is often associated with things like confusion or post-traumatic impact amnesia. So you forgot what happened immediately afterwards or you had a little bit of a time travel, as I like to call it.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So if you were unconscious for a couple of minutes, you probably had a mild traumatic brain injury. This is often associated with things like confusion or post-traumatic impact amnesia. So you forgot what happened immediately afterwards or you had a little bit of a time travel, as I like to call it.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And this can occur for a couple of hours or even up to one day is the general line that we cross there. The overwhelming majority of recreational and sport-related concussions fall into this category. Therefore, almost always, though not always, but almost always when you hear the word concussion, you can generally translate that into a mild TBI.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And this can occur for a couple of hours or even up to one day is the general line that we cross there. The overwhelming majority of recreational and sport-related concussions fall into this category. Therefore, almost always, though not always, but almost always when you hear the word concussion, you can generally translate that into a mild TBI.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Now, not all TBIs are concussions, but all concussions are TBIs. Okay, so one more time in case I lost you there. Concussion is effectively a mild traumatic brain injury based on those categories. If you had worse effects, so you were unconscious for longer or your amnesia will lasted longer, then you may be actually be considered to be in a moderate category.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Now, not all TBIs are concussions, but all concussions are TBIs. Okay, so one more time in case I lost you there. Concussion is effectively a mild traumatic brain injury based on those categories. If you had worse effects, so you were unconscious for longer or your amnesia will lasted longer, then you may be actually be considered to be in a moderate category.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So moderate technically is defined as a loss of consciousness or amnesia for somewhere between 30 minutes to up to 24 hours. Symptoms associated with this are more severe. It is headaches, confusion, dizziness, nausea, vomiting, slurred speech, drowsiness, difficulty concentrating, so on and so forth.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So moderate technically is defined as a loss of consciousness or amnesia for somewhere between 30 minutes to up to 24 hours. Symptoms associated with this are more severe. It is headaches, confusion, dizziness, nausea, vomiting, slurred speech, drowsiness, difficulty concentrating, so on and so forth.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And so another kind of back of the envelope way to differentiate between mild and moderate is mild, again, not always, but rough guidelines here. Mild is fairly acute. So in and immediately after the injury, you had symptoms, but then you're usually back to normal. Moderate often comes with downstream problems, not the injury themselves.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And so another kind of back of the envelope way to differentiate between mild and moderate is mild, again, not always, but rough guidelines here. Mild is fairly acute. So in and immediately after the injury, you had symptoms, but then you're usually back to normal. Moderate often comes with downstream problems, not the injury themselves.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So this is when you have behavioral changes because of the TBI. You've got, again, difficulty with memory that lasts a long time. That's, again, back of the envelope kind of distinction. If it is worse than that, we call it severe. That is technically a loss of consciousness or amnesia for somewhere between 24 hours to up to or more than seven days.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So this is when you have behavioral changes because of the TBI. You've got, again, difficulty with memory that lasts a long time. That's, again, back of the envelope kind of distinction. If it is worse than that, we call it severe. That is technically a loss of consciousness or amnesia for somewhere between 24 hours to up to or more than seven days.