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Dr. Andy Galpin

๐Ÿ‘ค Speaker
9972 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And I know because I grew up in the country and I've tried it all. It's easy to cook and tastes incredible, My wife and small kids absolutely inhale it. And the jerky sticks are a daily staple for me with 10 grams of protein and just 55 calories. I literally ate two just now and I send it to school with my kids all the time.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And I know because I grew up in the country and I've tried it all. It's easy to cook and tastes incredible, My wife and small kids absolutely inhale it. And the jerky sticks are a daily staple for me with 10 grams of protein and just 55 calories. I literally ate two just now and I send it to school with my kids all the time.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

While Maui Nui venison offers the highest quality meat available, there is a catch. Supplies are limited by nature. Responsible population management means they won't go beyond the harvest capacity. Memberships are the best way to ensure that you can get the meat you want whenever you want it, so be sure to secure your spot now. Visit mauinuivenison.com slash perform for 20% off.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

While Maui Nui venison offers the highest quality meat available, there is a catch. Supplies are limited by nature. Responsible population management means they won't go beyond the harvest capacity. Memberships are the best way to ensure that you can get the meat you want whenever you want it, so be sure to secure your spot now. Visit mauinuivenison.com slash perform for 20% off.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Again, that's mauinuivenison.com slash perform for 20% off. Let's jump right into it with our very first nutrient compound, and that's creatine monohydrate. You're probably sick of hearing me talk about it because I've been doing it for so many years, but it's for good reason. There's so much data on it. It is by far the most widely studied sports supplement, and it's not even close.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Again, that's mauinuivenison.com slash perform for 20% off. Let's jump right into it with our very first nutrient compound, and that's creatine monohydrate. You're probably sick of hearing me talk about it because I've been doing it for so many years, but it's for good reason. There's so much data on it. It is by far the most widely studied sports supplement, and it's not even close.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

It's been studied in every population, healthy, diseased, young, old, men, women, kids, so on and so forth. And there's really very limited side effects, if any, that have been reported. Now creatine itself is a naturally occurring derivative of three very specific amino acids, methionine, glycine, and arginine. These are really, really common.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

It's been studied in every population, healthy, diseased, young, old, men, women, kids, so on and so forth. And there's really very limited side effects, if any, that have been reported. Now creatine itself is a naturally occurring derivative of three very specific amino acids, methionine, glycine, and arginine. These are really, really common.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Creatine itself, I typically have talked about how it's stored in muscle and used as a great fuel source. But many people don't realize it's actually also stored in your liver, testes, and brain. The last one, of course, is where we're gonna pay our attention to today. Now it's stored in the brain so that it can be used as a very quick fuel source. Your gears should be turning at this point.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Creatine itself, I typically have talked about how it's stored in muscle and used as a great fuel source. But many people don't realize it's actually also stored in your liver, testes, and brain. The last one, of course, is where we're gonna pay our attention to today. Now it's stored in the brain so that it can be used as a very quick fuel source. Your gears should be turning at this point.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Remember, one of the primary issues we have with the TBI is that energy demand problem. And so it made a ton of sense to scientists very early on to say, okay, we know that we have energy issues. We know that the fastest way any of our tissues can make energy is through creatine monohydrate. And we know it's in store in the brain already. It makes sense to try that.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Remember, one of the primary issues we have with the TBI is that energy demand problem. And so it made a ton of sense to scientists very early on to say, okay, we know that we have energy issues. We know that the fastest way any of our tissues can make energy is through creatine monohydrate. And we know it's in store in the brain already. It makes sense to try that.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

to both prevent or reduce the risk of and then treat brain injuries. So it's no surprise when we look at the research here on both TBI as well as aging and normal brain health research to find that creatine monohydrate often improves cognitive function in both brain injury and normal healthy aging folks.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

to both prevent or reduce the risk of and then treat brain injuries. So it's no surprise when we look at the research here on both TBI as well as aging and normal brain health research to find that creatine monohydrate often improves cognitive function in both brain injury and normal healthy aging folks.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Now, it's not the world's most powerful nootropic, but it is effective and been shown again in many models and many studies across many laboratories. So because it's so effective at giving energy, especially in low oxygen situations, you'll see evidence across injury and TBI papers, but also just normal cognitive function in healthy individuals out to see benefit, right?

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

Now, it's not the world's most powerful nootropic, but it is effective and been shown again in many models and many studies across many laboratories. So because it's so effective at giving energy, especially in low oxygen situations, you'll see evidence across injury and TBI papers, but also just normal cognitive function in healthy individuals out to see benefit, right?

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So creatine is effective in all of those populations, and the physiology, biochemistry make total sense. Now, specifically regarding TBIs and concussions, one of the things you want to pay attention to a lot is what's called the second impact syndrome. Many people have not heard of this, but this is the basic idea of repeated head blows cause more damage, as time goes on.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

So creatine is effective in all of those populations, and the physiology, biochemistry make total sense. Now, specifically regarding TBIs and concussions, one of the things you want to pay attention to a lot is what's called the second impact syndrome. Many people have not heard of this, but this is the basic idea of repeated head blows cause more damage, as time goes on.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And so one of the things that's been shown with creatine is it is really effective for that second impact syndrome. More specifically, it's been shown that the repeated head blows cause more damage if the creatine is depleted prior to the additional impacts. Okay, so imagine you had one single impact, the more creatine depletion you have, the worse damage you get if you have a secondary impact.

Huberman Lab
Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

And so one of the things that's been shown with creatine is it is really effective for that second impact syndrome. More specifically, it's been shown that the repeated head blows cause more damage if the creatine is depleted prior to the additional impacts. Okay, so imagine you had one single impact, the more creatine depletion you have, the worse damage you get if you have a secondary impact.