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Dr. Andy Galpin

๐Ÿ‘ค Speaker
9972 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

They have more mitochondria.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And they're overall good at what we call anti-gravity or postural.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

So when you think about slow twitch fibers, they tend to be the ones that are on kind of all day, keep you upright and erect, keep you moving, and keep you at a low level of contraction, but continuously.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Fast twitch fibers, particularly the 2A fibers, are really the opposite.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

So they're going to be hedged more towards fast speed of contraction.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

But really, they're not particularly effective at fatigue resistance.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

They are going to prefer using things like phosphocreatine or carbohydrates as a fuel source and are not as effective at things like fat or long-term sustained contractions.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

The third and final type, 2X, are the fastest of the bunch.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

While your 2A and fast-twitch fibers are somewhere in the neighborhood of five to six times more powerful than a slower type 1 fiber, a 2X fiber is in the neighborhood of 20 times more powerful.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

The downside is we don't really have any good evidence of normal humans having many, if any, pure 2X fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Oddly enough, we see it in extreme muscle disuse situations, things like spinal cord injury or coming back from extended space flight or situations like that.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And so there's a lot of mystery still behind these 2X fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

We could get into that again in maybe more detail a little bit later.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

So on its surface, while we really have these three distinct unique fiber types, type 1, type 2A, and type 2X, it is really appropriate to discuss basically the type 1 and the type 2As from now on.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Now, within any individual muscle you have on your body, the proportion of fast twitch to slow twitch, in other words, the amount of fast or slow twitch fibers in that muscle, varies widely from muscle to muscle, as well as from human to human.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Now, that actually determines a lot about the function of that muscle.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

For example, if you take, say, the soleus muscle, which is one of the small muscles kind of behind the back of your calf there that goes into the bottom of your heel.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

That is heavily based towards slow twitch muscle fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

Depending on the person, it would be something in the neighborhood of 70% to all the way up to 90 plus percent slow twitch fibers.

Huberman Lab
Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

And that's because the primary purpose of the soleus is to keep you standing and moving all day.