Dr. Aseem Malhotra
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how you can actually explain that mark because one way of looking at the statistics looking at industry sponsored trials which we've already alluded to should be taken with a grain of salt because they are best case scenario they're curated information or a tab of butter maybe well yeah actually absolutely butter would be better remind me to come back about a butter story and me being hauled into a medical director's office to talk about butter by the way um when i busted the myth of saturated fat and heart disease you know when you look at the data
from industry-sponsored trials, and you look at the statistics that looks at the average or median increase in life expectancy over five years, right, in the highest risk groups where there is a greater benefit, the median increase in life expectancy over a five-year period in the person that's had a heart attack, right, and say in their 50s,
from industry-sponsored trials, and you look at the statistics that looks at the average or median increase in life expectancy over five years, right, in the highest risk groups where there is a greater benefit, the median increase in life expectancy over a five-year period in the person that's had a heart attack, right, and say in their 50s,
from industry-sponsored trials, and you look at the statistics that looks at the average or median increase in life expectancy over five years, right, in the highest risk groups where there is a greater benefit, the median increase in life expectancy over a five-year period in the person that's had a heart attack, right, and say in their 50s,
If you look at the median increase in life expectancy in that group, another way that we use in medicine when we talk about informed consent or I call it ethical, very controversial topic, ethical evidence-based medical practice. Which means true informed consent, which means telling patients the numbers needed to treat are their absolute individual benefit.
If you look at the median increase in life expectancy in that group, another way that we use in medicine when we talk about informed consent or I call it ethical, very controversial topic, ethical evidence-based medical practice. Which means true informed consent, which means telling patients the numbers needed to treat are their absolute individual benefit.
If you look at the median increase in life expectancy in that group, another way that we use in medicine when we talk about informed consent or I call it ethical, very controversial topic, ethical evidence-based medical practice. Which means true informed consent, which means telling patients the numbers needed to treat are their absolute individual benefit.
And you look at the totality of evidence. I know there are lots of studies we can talk about, but for me, it's about what does the totality of evidence tell us, right? And there's a great website, which is independently evaluated by doctors, and it goes through peer review in one of the... family physician journals in the US called the NNT.com. Numbers Needed to Treat. People can look it up.
And you look at the totality of evidence. I know there are lots of studies we can talk about, but for me, it's about what does the totality of evidence tell us, right? And there's a great website, which is independently evaluated by doctors, and it goes through peer review in one of the... family physician journals in the US called the NNT.com. Numbers Needed to Treat. People can look it up.
And you look at the totality of evidence. I know there are lots of studies we can talk about, but for me, it's about what does the totality of evidence tell us, right? And there's a great website, which is independently evaluated by doctors, and it goes through peer review in one of the... family physician journals in the US called the NNT.com. Numbers Needed to Treat. People can look it up.
It's great. It's a free website.
It's great. It's a free website.
It's great. It's a free website.
Yeah. Or you take paracetamol for a headache, it's like one in two. So it's like two. Right. Two people, one will get their headache completely resolved with paracetamol.
Yeah. Or you take paracetamol for a headache, it's like one in two. So it's like two. Right. Two people, one will get their headache completely resolved with paracetamol.
Yeah. Or you take paracetamol for a headache, it's like one in two. So it's like two. Right. Two people, one will get their headache completely resolved with paracetamol.
Yeah, so it's actually, so I know this stuff inside out. So if you've had a heart attack already, let's take the high-risk group, you have to treat 83 people over five years for one to have their life saved or life prolonged, right, okay? And for preventing a further heart attack, one in 39. Now, most people around the world, Mark, who are prescribed statins are not in that group.
Yeah, so it's actually, so I know this stuff inside out. So if you've had a heart attack already, let's take the high-risk group, you have to treat 83 people over five years for one to have their life saved or life prolonged, right, okay? And for preventing a further heart attack, one in 39. Now, most people around the world, Mark, who are prescribed statins are not in that group.
Yeah, so it's actually, so I know this stuff inside out. So if you've had a heart attack already, let's take the high-risk group, you have to treat 83 people over five years for one to have their life saved or life prolonged, right, okay? And for preventing a further heart attack, one in 39. Now, most people around the world, Mark, who are prescribed statins are not in that group.
They are in the either low risk... 75%, right? Yeah, exactly. Low risk or what we call high risk primary prevention. Now, the benefits of a statin over a five-year period in that group, at best, is 1% in preventing a non-fatal heart attack, a non-disabling stroke, okay? But without prolonging...