Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

Dr. Ben Bikman

๐Ÿ‘ค Speaker
1894 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

There's fat and there's glucose, which are the two building blocks for triglycerides within the fat cell itself. The triglycerides which are kind of giving the fat cell its big fat blob, or what we call a lipid droplet. And so again, the fat cells are surrounded by calories, an abundance of energy, and yet they're small.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

There's fat and there's glucose, which are the two building blocks for triglycerides within the fat cell itself. The triglycerides which are kind of giving the fat cell its big fat blob, or what we call a lipid droplet. And so again, the fat cells are surrounded by calories, an abundance of energy, and yet they're small.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

There's no changes on those fat cells until we start sprinkling in insulin into the culture, into the bath, the medium we call it, the liquid that the cells are bathing in. Once we start putting in insulin, now the fat cells know what to do, which is store the energy. So that's a part that's so often overlooked. And this doesn't apply to all metabolism in all cells, but

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

There's no changes on those fat cells until we start sprinkling in insulin into the culture, into the bath, the medium we call it, the liquid that the cells are bathing in. Once we start putting in insulin, now the fat cells know what to do, which is store the energy. So that's a part that's so often overlooked. And this doesn't apply to all metabolism in all cells, but

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

There's no changes on those fat cells until we start sprinkling in insulin into the culture, into the bath, the medium we call it, the liquid that the cells are bathing in. Once we start putting in insulin, now the fat cells know what to do, which is store the energy. So that's a part that's so often overlooked. And this doesn't apply to all metabolism in all cells, but

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It is a pretty central theme that cells need to be told what to do with the energy they have available. Whether it's energy available on the outside to come in, or whether it's energy that the cell already has available within itself, it's the

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It is a pretty central theme that cells need to be told what to do with the energy they have available. Whether it's energy available on the outside to come in, or whether it's energy that the cell already has available within itself, it's the

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It is a pretty central theme that cells need to be told what to do with the energy they have available. Whether it's energy available on the outside to come in, or whether it's energy that the cell already has available within itself, it's the

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Hormones, it's hormones like insulin or glucagon or epinephrine, adrenaline, and others, growth hormone, that signal to the cell what to do with the energy that it has access to. The cell doesn't just know what to do with the energy. The hormones are what's sort of sampling the entire body understanding what's going on in the entire body, and then dictating individual cells.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Hormones, it's hormones like insulin or glucagon or epinephrine, adrenaline, and others, growth hormone, that signal to the cell what to do with the energy that it has access to. The cell doesn't just know what to do with the energy. The hormones are what's sort of sampling the entire body understanding what's going on in the entire body, and then dictating individual cells.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

Hormones, it's hormones like insulin or glucagon or epinephrine, adrenaline, and others, growth hormone, that signal to the cell what to do with the energy that it has access to. The cell doesn't just know what to do with the energy. The hormones are what's sort of sampling the entire body understanding what's going on in the entire body, and then dictating individual cells.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It's like the hormones are the conductor to the orchestra. Any individual section, the brass, the woodwinds, the percussion, they don't know what notes to play on their own. They need something to tell them when to come in, the pace, the volume. The hormones are the conductors of the orchestra. And when it comes to fat cell growth,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It's like the hormones are the conductor to the orchestra. Any individual section, the brass, the woodwinds, the percussion, they don't know what notes to play on their own. They need something to tell them when to come in, the pace, the volume. The hormones are the conductors of the orchestra. And when it comes to fat cell growth,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

It's like the hormones are the conductor to the orchestra. Any individual section, the brass, the woodwinds, the percussion, they don't know what notes to play on their own. They need something to tell them when to come in, the pace, the volume. The hormones are the conductors of the orchestra. And when it comes to fat cell growth,

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

You have on one side the hormone insulin, which is overwhelmingly promoting the growth of the fat cell, and it is so powerful in its own right that it is offset by multiple other hormones that tend to have a catabolic effect to insulin's anabolic effect. like some of the other ones I mentioned, glucagon and epinephrine, most obviously, and growth hormone.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

You have on one side the hormone insulin, which is overwhelmingly promoting the growth of the fat cell, and it is so powerful in its own right that it is offset by multiple other hormones that tend to have a catabolic effect to insulin's anabolic effect. like some of the other ones I mentioned, glucagon and epinephrine, most obviously, and growth hormone.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

You have on one side the hormone insulin, which is overwhelmingly promoting the growth of the fat cell, and it is so powerful in its own right that it is offset by multiple other hormones that tend to have a catabolic effect to insulin's anabolic effect. like some of the other ones I mentioned, glucagon and epinephrine, most obviously, and growth hormone.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

So there are a handful of hormones that are trying to get the fat cell to shrink and share its energy, all to try to offset the incredible power of insulin, which is telling the fat cell to store energy. But insulin goes even further than that.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

So there are a handful of hormones that are trying to get the fat cell to shrink and share its energy, all to try to offset the incredible power of insulin, which is telling the fat cell to store energy. But insulin goes even further than that.

Dhru Purohit Show
The Labs You Need Your Doctor to Run to Know if Your Metabolically Healthy

So there are a handful of hormones that are trying to get the fat cell to shrink and share its energy, all to try to offset the incredible power of insulin, which is telling the fat cell to store energy. But insulin goes even further than that.