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Dr. Brad McGregor

๐Ÿ‘ค Speaker
290 total appearances

Appearances Over Time

Podcast Appearances

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And so it really established a new standard of care.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Now, at the same time, there's a ton of questions that we now answer ourselves.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

It's like, do we really need to have pre- and post-op therapy?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

A third of patients did not get adjuvant therapy.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Why did they not get adjuvant therapy?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What happened to those patients?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What's that breakdown?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

I think those are going to be key questions.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

As we look to the future, all we know is past CR versus no past CR.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What were those no past CR breakdowns?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Were those some TA, T1, CAS?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What actually was being seen there?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

What about CTA?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

We see a really nice analysis from Agra.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

Are we going to see the same thing here?

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

So a lot of unanswered questions.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

But at the same time, I think it really does tell us that we now have a highly effective systemic therapy

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

offer in the perioperative setting to patients who are in that cisplatin-based therapy.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And the only way we're going to offer that patient is if we see those patients.

BackTable Urology
Ep. 287 Urothelial Carcinoma: Understanding CTDNA and Precision Medicine with Dr. Amanda Nizam and Dr. Brad McGregor

And so I think it's just critical that medical oncology be involved with all patients with muscle-based hepatic cancer early on in that treatment course.