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Dr. Casey Halpern

๐Ÿ‘ค Speaker
312 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

So we have so much work to do there.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

Eating disorders and TMS have been so sort of scarcely studied or there've been such little research done in that space.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

And so it is an area that we need to work on.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

So ultrasound right now, transcranial magnetic resonance guided focus ultrasound.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

So this is an FDA approved method to deliver an ablation to the brain non-invasively.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

There are researchers, myself included, that are trying to use transcranial magnetic-guided, magnetic resonance-guided focused ultrasound, or MRI-guided focused ultrasound, to use it in a modulatory way, not just as an ablation, but to drive neuronal activity, or inhibit it, perhaps.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

We're still learning how to do that.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

There are trials that are trying to understand if you can use ultrasound to open the blood-brain barrier so you can deliver a medication to that specific area.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

perhaps for a brain tumor or something like that.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

So it's a very exciting field and it is FDA approved for tremor right now.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

And so I actually do it routinely for patients with tremor with Parkinson's or essential tremor.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

And so I love doing it.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

It's often just kind of a miracle because there's no incision.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

I don't have to place an electrode into the brain to achieve a similar result.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

It's fabulously effective for these patients.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

It treats patients on one side, usually their dominant hand or their worst hand.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

And it really speaks to the fact that, wow, you can deliver noninvasively an ablation to the brain in a hypothesized zone that we think is related to the problem at hand.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

And at least with tremor, it works really well.

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

Could this be effective for psychiatric disease, obesity, eating disorders?

Huberman Lab
Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

Well, perhaps.