Dr. Chris Palmer

A cell can't do what it's supposed to do without mitochondria. The other concept that you mentioned, neuroplasticity, neuroplasticity is all about energy and metabolic resources to create new connections, new neural connections between axons, dendrites, somas, other aspects of neurons and cells and other types of cells, astrocytes, oligodendrocytes.

A cell can't do what it's supposed to do without mitochondria. The other concept that you mentioned, neuroplasticity, neuroplasticity is all about energy and metabolic resources to create new connections, new neural connections between axons, dendrites, somas, other aspects of neurons and cells and other types of cells, astrocytes, oligodendrocytes.

A cell can't do what it's supposed to do without mitochondria. The other concept that you mentioned, neuroplasticity, neuroplasticity is all about energy and metabolic resources to create new connections, new neural connections between axons, dendrites, somas, other aspects of neurons and cells and other types of cells, astrocytes, oligodendrocytes.

But in order to get neuroplasticity, neuroplasticity implies growth and modulation and even pruning, but it involves change. And in order for a living organism to change, that requires this foundational concept of metabolism. Now, on the surface, to a lot of people, that sounds too abstract.

But in order to get neuroplasticity, neuroplasticity implies growth and modulation and even pruning, but it involves change. And in order for a living organism to change, that requires this foundational concept of metabolism. Now, on the surface, to a lot of people, that sounds too abstract.

But in order to get neuroplasticity, neuroplasticity implies growth and modulation and even pruning, but it involves change. And in order for a living organism to change, that requires this foundational concept of metabolism. Now, on the surface, to a lot of people, that sounds too abstract.

And it sounds like, well, that's ridiculous then, if you're saying that metabolism is everything in biology. And I kind of am. Of course it is. You can't talk about biology without talking about metabolism. But when you talk about metabolic health, it becomes much more concrete, pragmatic, and real when with real tools that you talk about all of the time on this podcast.

And it sounds like, well, that's ridiculous then, if you're saying that metabolism is everything in biology. And I kind of am. Of course it is. You can't talk about biology without talking about metabolism. But when you talk about metabolic health, it becomes much more concrete, pragmatic, and real when with real tools that you talk about all of the time on this podcast.

And it sounds like, well, that's ridiculous then, if you're saying that metabolism is everything in biology. And I kind of am. Of course it is. You can't talk about biology without talking about metabolism. But when you talk about metabolic health, it becomes much more concrete, pragmatic, and real when with real tools that you talk about all of the time on this podcast.

Exercise promotes metabolic health. Exercise promotes neuroplasticity. They are inseparable. You can't improve your metabolic health without also at least opening up the opportunity for neuroplasticity Improving your diet does the same thing. Sleep or lack thereof can impact this. Substance use can impact this. And so, you know, in a way, it basically says, let's connect all of the dots.

Exercise promotes metabolic health. Exercise promotes neuroplasticity. They are inseparable. You can't improve your metabolic health without also at least opening up the opportunity for neuroplasticity Improving your diet does the same thing. Sleep or lack thereof can impact this. Substance use can impact this. And so, you know, in a way, it basically says, let's connect all of the dots.

Exercise promotes metabolic health. Exercise promotes neuroplasticity. They are inseparable. You can't improve your metabolic health without also at least opening up the opportunity for neuroplasticity Improving your diet does the same thing. Sleep or lack thereof can impact this. Substance use can impact this. And so, you know, in a way, it basically says, let's connect all of the dots.

Let's not hyper-focus on serotonin and a serotonin imbalance or deficiency as the singular cause of depression. Because for those of you who don't know, that is ridiculously... reductionistic. And it is absolutely not true. We know that. We know that with certainty now.

Let's not hyper-focus on serotonin and a serotonin imbalance or deficiency as the singular cause of depression. Because for those of you who don't know, that is ridiculously... reductionistic. And it is absolutely not true. We know that. We know that with certainty now.

Let's not hyper-focus on serotonin and a serotonin imbalance or deficiency as the singular cause of depression. Because for those of you who don't know, that is ridiculously... reductionistic. And it is absolutely not true. We know that. We know that with certainty now.

You know, the whole serotonin hypothesis of depression came about not because researchers identified serotonin deficits in the brain. That entire concept came from the observation that medications that modulate serotonin activity or inhibit its reuptake into neurons, those medications, SSRIs, other types of antidepressants, those medications can reduce the symptoms of depression in some people.

You know, the whole serotonin hypothesis of depression came about not because researchers identified serotonin deficits in the brain. That entire concept came from the observation that medications that modulate serotonin activity or inhibit its reuptake into neurons, those medications, SSRIs, other types of antidepressants, those medications can reduce the symptoms of depression in some people.

You know, the whole serotonin hypothesis of depression came about not because researchers identified serotonin deficits in the brain. That entire concept came from the observation that medications that modulate serotonin activity or inhibit its reuptake into neurons, those medications, SSRIs, other types of antidepressants, those medications can reduce the symptoms of depression in some people.

That was just a purely serendipitous finding. It was serendipity. The first antidepressant was actually a tuberculosis treatment. They were giving it to patients on a tuberculosis ward. And an astute infectious disease doctor noticed some of these patients are really depressed. But when I give them this tuberculosis treatment, they perk up.

That was just a purely serendipitous finding. It was serendipity. The first antidepressant was actually a tuberculosis treatment. They were giving it to patients on a tuberculosis ward. And an astute infectious disease doctor noticed some of these patients are really depressed. But when I give them this tuberculosis treatment, they perk up.