Dr. Chris Palmer

So we have a really good longitudinal study of children. So researchers followed over 5,000 kids from birth to age 24. So even before they have obesity, they have insulin resistance, which we can measure. The children at age nine who had the highest levels of insulin resistance were five times more likely, it's 500% more likely to develop a psychotic disorder. Holy cow. By the time they were 24.

So we have a really good longitudinal study of children. So researchers followed over 5,000 kids from birth to age 24. So even before they have obesity, they have insulin resistance, which we can measure. The children at age nine who had the highest levels of insulin resistance were five times more likely, it's 500% more likely to develop a psychotic disorder. Holy cow. By the time they were 24.

Wow. That's bipolar disorder or schizophrenia. The children who gained the most weight around the time of puberty, four times more likely to have major depression by the time they turn 24. You could mix and match those statistics, but those were the statistically significant findings.

Wow. That's bipolar disorder or schizophrenia. The children who gained the most weight around the time of puberty, four times more likely to have major depression by the time they turn 24. You could mix and match those statistics, but those were the statistically significant findings.

Wow. That's bipolar disorder or schizophrenia. The children who gained the most weight around the time of puberty, four times more likely to have major depression by the time they turn 24. You could mix and match those statistics, but those were the statistically significant findings.

But children who gained a lot of weight around puberty were also more likely to develop psychotic disorders and all sorts of other disorders. And likewise, children with high levels of insulin resistance More likely to develop mood disorders and other disorders But the bottom line is that and a five-fold increased risk.

But children who gained a lot of weight around puberty were also more likely to develop psychotic disorders and all sorts of other disorders. And likewise, children with high levels of insulin resistance More likely to develop mood disorders and other disorders But the bottom line is that and a five-fold increased risk.

But children who gained a lot of weight around puberty were also more likely to develop psychotic disorders and all sorts of other disorders. And likewise, children with high levels of insulin resistance More likely to develop mood disorders and other disorders But the bottom line is that and a five-fold increased risk.

I want to be clear When we talk about statistics like oh, maybe eating so much red meat is bad for you Those epidemiological studies at best find 10% 15% increased risk over years We're talking 500% increased risk. This is not trivial. This is like slap in the face. This is a stronger connection than genes, genetics, than family history, than other things.

I want to be clear When we talk about statistics like oh, maybe eating so much red meat is bad for you Those epidemiological studies at best find 10% 15% increased risk over years We're talking 500% increased risk. This is not trivial. This is like slap in the face. This is a stronger connection than genes, genetics, than family history, than other things.

I want to be clear When we talk about statistics like oh, maybe eating so much red meat is bad for you Those epidemiological studies at best find 10% 15% increased risk over years We're talking 500% increased risk. This is not trivial. This is like slap in the face. This is a stronger connection than genes, genetics, than family history, than other things.

I think there's truth in, there are some risk genes that we have identified. And interestingly, almost all of them can be linked directly to metabolism or specifically mitochondria. We can get into the nerdy biology if you want, but almost all of them can be linked to metabolic health.

I think there's truth in, there are some risk genes that we have identified. And interestingly, almost all of them can be linked directly to metabolism or specifically mitochondria. We can get into the nerdy biology if you want, but almost all of them can be linked to metabolic health.

I think there's truth in, there are some risk genes that we have identified. And interestingly, almost all of them can be linked directly to metabolism or specifically mitochondria. We can get into the nerdy biology if you want, but almost all of them can be linked to metabolic health.

I believe we can. Wow. And that is... That's huge. That, in my mind, is the hope.

I believe we can. Wow. And that is... That's huge. That, in my mind, is the hope.

I believe we can. Wow. And that is... That's huge. That, in my mind, is the hope.

There is... So we don't have massive, randomized clinical trials with thousands of patients yet.

There is... So we don't have massive, randomized clinical trials with thousands of patients yet.

There is... So we don't have massive, randomized clinical trials with thousands of patients yet.