Dr. Chris van Tulleken
๐ค SpeakerAppearances Over Time
Podcast Appearances
All of the fMRI data that you generate from any experiment is hard to be really sure of what's causing what, but we saw very significant changes and it's notable they were between those two regions. And bear in mind, I was 43 when I was โ it was a few years ago. I was in my mid-40s doing it.
All of the fMRI data that you generate from any experiment is hard to be really sure of what's causing what, but we saw very significant changes and it's notable they were between those two regions. And bear in mind, I was 43 when I was โ it was a few years ago. I was in my mid-40s doing it.
You know, what is โ it raises the question of these kind of brain changes to children who are eating much more UPF over a more prolonged period of time. And then the other โ in a way, the change I was most fascinated by โ well, there were two others, but the physical change โ was that we measured my satiety, my hormone response to a normal meal. So this isn't something you can fake.
You know, what is โ it raises the question of these kind of brain changes to children who are eating much more UPF over a more prolonged period of time. And then the other โ in a way, the change I was most fascinated by โ well, there were two others, but the physical change โ was that we measured my satiety, my hormone response to a normal meal. So this isn't something you can fake.
You know, what is โ it raises the question of these kind of brain changes to children who are eating much more UPF over a more prolonged period of time. And then the other โ in a way, the change I was most fascinated by โ well, there were two others, but the physical change โ was that we measured my satiety, my hormone response to a normal meal. So this isn't something you can fake.
We would, at the beginning of the experiment, I went and I ate a standardized meal and we measured changes in the hormones you see, you have fullness hormones and hunger hormones, they go up, down.
We would, at the beginning of the experiment, I went and I ate a standardized meal and we measured changes in the hormones you see, you have fullness hormones and hunger hormones, they go up, down.
We would, at the beginning of the experiment, I went and I ate a standardized meal and we measured changes in the hormones you see, you have fullness hormones and hunger hormones, they go up, down.
And what we see is that after eating the same standard meal at the end of the UPF diet, my fullness hormones went up much less and my hunger hormones stayed much higher. So at the end of the same meal... So the diet... is modifying your body's ability to feel full after any food. And that to me was the most kind of significant thing.
And what we see is that after eating the same standard meal at the end of the UPF diet, my fullness hormones went up much less and my hunger hormones stayed much higher. So at the end of the same meal... So the diet... is modifying your body's ability to feel full after any food. And that to me was the most kind of significant thing.
And what we see is that after eating the same standard meal at the end of the UPF diet, my fullness hormones went up much less and my hunger hormones stayed much higher. So at the end of the same meal... So the diet... is modifying your body's ability to feel full after any food. And that to me was the most kind of significant thing.
It's not just that the food doesn't fill you up, but we think it may be having changes about the whole way you handle food and feel full at the end of meals. Really important to say, I know I'm one participant. That's why we've turned it into a big registered clinical trial funded by our research council and an independent research trust.
It's not just that the food doesn't fill you up, but we think it may be having changes about the whole way you handle food and feel full at the end of meals. Really important to say, I know I'm one participant. That's why we've turned it into a big registered clinical trial funded by our research council and an independent research trust.
It's not just that the food doesn't fill you up, but we think it may be having changes about the whole way you handle food and feel full at the end of meals. Really important to say, I know I'm one participant. That's why we've turned it into a big registered clinical trial funded by our research council and an independent research trust.
And that's why we're doing it robustly with ethics permission as a registered trial. Kevin Hall is one. How many people are in that trial? There are two arms and we're doing, how many have we registered? Somewhere over 30, I think. So it's not a huge trial. It's a bit bigger than Kevin's.
And that's why we're doing it robustly with ethics permission as a registered trial. Kevin Hall is one. How many people are in that trial? There are two arms and we're doing, how many have we registered? Somewhere over 30, I think. So it's not a huge trial. It's a bit bigger than Kevin's.
And that's why we're doing it robustly with ethics permission as a registered trial. Kevin Hall is one. How many people are in that trial? There are two arms and we're doing, how many have we registered? Somewhere over 30, I think. So it's not a huge trial. It's a bit bigger than Kevin's.
Well, of course, so the way the trial is designed is we're actually feeding, we're trying to feed people the healthiest ultra processed food versus a minimally processed diet. So our We didn't feel it was ethical for them to just eat any old ultra processed food. I think the jury is in on that evidence.
Well, of course, so the way the trial is designed is we're actually feeding, we're trying to feed people the healthiest ultra processed food versus a minimally processed diet. So our We didn't feel it was ethical for them to just eat any old ultra processed food. I think the jury is in on that evidence.
Well, of course, so the way the trial is designed is we're actually feeding, we're trying to feed people the healthiest ultra processed food versus a minimally processed diet. So our We didn't feel it was ethical for them to just eat any old ultra processed food. I think the jury is in on that evidence.