Dr. Darren Candow

So super excited to see where this is going for the next 20 or 30 years.

Yeah.

And that's probably the best overall segue.

So it increases brain bioenergetics.

And if it can, one of the common numbers with depression or concussion is that they have reduced brain creatine stores and bioenergetics compared to a healthy control on average.

And so maybe creatine is bringing those values up or even slightly more.

And now the brain has more energy capacity to do and deal with all the daily stressors of society.

Absolutely.

Yeah.

Yeah, so I'm now in the camp, and I think a lot of other researchers, and a lot of the work's coming from here in the United States, but if you're in contact sports, creatine should be taken on a daily basis because, unfortunately, if you do get hit, in the rodent model, because you can't do this in humans, but when they've actually forced concussion in rodents taking creatine beforehand, the recovery symptoms are really accelerated.

And in the only single human study was in children,

As soon as these people in Scotland got head trauma, they put them on 0.4 grams of creatine per kilogram.

So about 20 – these are just children immediately.

And over six months, these children that were taking creatine had substantial improvements in self-care and efficacy.

No blood biomarkers were taken, but at least it showed the improvement in recovery.

So –

Instead of waiting until you get hit, why not take the preventative role?

And that's why, again, I think for me, and again, it's opinion, but we've seen some data to suggest that 10 grams might be a good viable dose, more or even a little bit less, depending on why you're taking it.

But I personally take it from a whole body perspective.

I don't play any contact sports now, but who knows?