#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
I think what happened was in the inception of creating research, a lot of people were not drinking water or going through some practices like wrestling, wearing rubber suits, extreme hydration.
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
So we've looked at study after study and rest assured from a clinical perspective, creatine does not adversely affect renal, liver, or cardiovascular cells.
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
The theory here was that when creatine enters your muscle, when it gets metabolized, it's non-enzymatically metabolized to something called creatinine.
#100 The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
So unfortunately, when a lot of people go to their doctor, they don't say, hey, to the nephrologist or GP, I'm on creatine supplements because it's logical that if you're taking creatine, your creatinine might be acutely raised.