Dr. Darren Candow
👤 SpeakerAppearances Over Time
Podcast Appearances
Now, that could be the dose there, but you're totally right.
Methionine is donating...
I think it's 40% of our methyl groups to creatine synthesis.
So if I'm taking more dietary creatine or supplementation, why use that?
Why not decrease the amount being synthesized?
Because that has huge implications on endothelial health and cardiovascular health.
But ironically, it's not even equivocal.
The majority suggests it doesn't decrease.
Maybe the studies are not long enough, or maybe they're not in populations that need it as much yet.
Right.
Correct.
Yeah.
And it's easy to do.
You just look at some of these blood biomarkers.
But there's not a lot of, there's probably less than 10, majority in rodents, a few in human.
And I think last time I checked, it was probably seven against, three supported it.
So there's a lot of methodology issues there.
Absolutely.
Especially as we start to get into the vascular health, for sure.
That's a huge area.