Dr. Darren Candow

I'd like it to be higher just because of some of the new data to suggest every day we get out of bed, we're a day older.

There's some good evidence to suggest bone needs a bit more.

And of course, the brain, we still don't know.

But I have some lines of thinking about when we're really metabolically stressed, how much to take.

But if you're taking five, rest assured, you're doing exceptionally well.

By two ways, a direct and indirect.

So let's go with the boring direct.

It sort of increases osteoblast cells.

These are the cells that sort of create or the formation of our bone cells.

So in rodents, osteoblast cells have been energized in the presence of creatine.

So it was logical to think in humans, maybe our osteoblast cells, the cells that are responsible for increasing bone size and strength,

might have more fuel, and these cells do use creatine just like our muscles do for fuel, and potentially increase bone density.

And if that's true, we've just cured osteoporosis, basically.

The other line of thinking, which is surprising, going back to this anti-catabolic phenomenon, is the best lines of evidence with bone are from an anti-catabolic perspective.

It seems to resemble a bisphosphonate.

So a lot of viewers are maybe taking a bisphosphonate.

It sort of preserves your skeleton.

I know my mom is taking that as well.

So creatine reduces something called the osteoclast activity or bone resorption.

So for some reason, it really inhibits these osteoclasts from sort of chopping down our bone and increasing blood calcium levels when not needed.