Dr. Darshan Shah
๐ค SpeakerAppearances Over Time
Podcast Appearances
Right, right. So, you know, I love what Function Health is doing with measuring LP little a. Like, I can't tell you the number of patients I see that still go to their primary doctors and have never had an LP little a done before. And they're wondering why they have so much heart disease.
Right, right. So, you know, I love what Function Health is doing with measuring LP little a. Like, I can't tell you the number of patients I see that still go to their primary doctors and have never had an LP little a done before. And they're wondering why they have so much heart disease.
Right, right. So, you know, I love what Function Health is doing with measuring LP little a. Like, I can't tell you the number of patients I see that still go to their primary doctors and have never had an LP little a done before. And they're wondering why they have so much heart disease.
When up to 15 to 20% of people have the genetic malformation that causes LP little a. And LP little a, just for the listeners to know, is a particularly aggressive form of cholesterol that causes... plaques in your arteries, but also can cause deposition of calcium on your blood valves. It can cause plaques in your arteries going to your brain. It's really dangerous.
When up to 15 to 20% of people have the genetic malformation that causes LP little a. And LP little a, just for the listeners to know, is a particularly aggressive form of cholesterol that causes... plaques in your arteries, but also can cause deposition of calcium on your blood valves. It can cause plaques in your arteries going to your brain. It's really dangerous.
When up to 15 to 20% of people have the genetic malformation that causes LP little a. And LP little a, just for the listeners to know, is a particularly aggressive form of cholesterol that causes... plaques in your arteries, but also can cause deposition of calcium on your blood valves. It can cause plaques in your arteries going to your brain. It's really dangerous.
It can cause heart attacks quite easily and strokes quite easily as well, and valve damage. And so if you have LP little a, you want to get it treated. Guess how you treat it? There's no treatment right now. There's no drug. Lifestyle changes, actually, this is resistant to lifestyle changes.
It can cause heart attacks quite easily and strokes quite easily as well, and valve damage. And so if you have LP little a, you want to get it treated. Guess how you treat it? There's no treatment right now. There's no drug. Lifestyle changes, actually, this is resistant to lifestyle changes.
It can cause heart attacks quite easily and strokes quite easily as well, and valve damage. And so if you have LP little a, you want to get it treated. Guess how you treat it? There's no treatment right now. There's no drug. Lifestyle changes, actually, this is resistant to lifestyle changes.
Yeah, natokinase I think is good.
Yeah, natokinase I think is good.
Yeah, natokinase I think is good.
It's not easy, right? People struggle with it. So we have two or three patients that we're treating with LP little a. Just like the toxins and the other things that we're talking about, all cholesterol also lives in your plasma, including the LP little a particles. And so this is removed in that bag of plasma that we're throwing away.
It's not easy, right? People struggle with it. So we have two or three patients that we're treating with LP little a. Just like the toxins and the other things that we're talking about, all cholesterol also lives in your plasma, including the LP little a particles. And so this is removed in that bag of plasma that we're throwing away.
It's not easy, right? People struggle with it. So we have two or three patients that we're treating with LP little a. Just like the toxins and the other things that we're talking about, all cholesterol also lives in your plasma, including the LP little a particles. And so this is removed in that bag of plasma that we're throwing away.
And so what we're finding in these two particular patients is that their LP little a actually stays close to normal levels for about six weeks after a plasma exchange. And so look, I mean, I think it's one of those therapies that as it becomes more ubiquitous, more people can use it for control of LP little a until we find a therapeutic that works.
And so what we're finding in these two particular patients is that their LP little a actually stays close to normal levels for about six weeks after a plasma exchange. And so look, I mean, I think it's one of those therapies that as it becomes more ubiquitous, more people can use it for control of LP little a until we find a therapeutic that works.
And so what we're finding in these two particular patients is that their LP little a actually stays close to normal levels for about six weeks after a plasma exchange. And so look, I mean, I think it's one of those therapies that as it becomes more ubiquitous, more people can use it for control of LP little a until we find a therapeutic that works.
There's a lot of research being done for therapeutics that works, but this is a great way to temporary control.
There's a lot of research being done for therapeutics that works, but this is a great way to temporary control.