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Dr. David Fajgenbaum

๐Ÿ‘ค Speaker
1737 total appearances

Appearances Over Time

Podcast Appearances

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

identify about, I think it's about 60 or 70 right now that have gotten what we call a deep dive where an MD or a PhD or an MD PhD trained person will really try to understand what are all the data for or against, like why would this drug likely work or not work?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

And then out of those 60 or so who have done deep dives, about 15 of those have then basically taken down to where we have a good plan.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

We think that if we do this clinical trial, we're gonna be able to unlock this drug helping a lot of kids or adults.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

And then out of those, I mentioned now like the nine active programs that we're moving forward.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

So we started as a non-private three years ago.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

We spent most of our first year doing fundraising, most of our second year really building on our infrastructure.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

It's really only been about one year where we've had the team working hard, going through all these scores.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

And so the opportunities I think are so huge.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

How do you find the patients to do the studies on?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

Yeah, so once we find a match that we think looks really promising, the next thing we do is find out who are the disease experts and who are the doctors that see the most patients?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

Is there a disease group?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

For a lot of these diseases, there's a parent of a kid with a disease where they've rallied around and created a nonprofit for that disease.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

We want to get in touch with them and understand their disease more.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

We want to understand what's missing.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

Could this drug really make a difference?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

And when we connect with them, it's like, we want to help your kid's condition or your condition.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

You know, will you work with us?

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

You know, we've raised money from the U.S.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

government and from philanthropists and foundations.

The Shawn Ryan Show
#240 Dr. David Fajgenbaum - Can AI Find Cures to Rare Diseases Using Existing Medicine?

You know, we're going to bring some money into here.