Dr. David Fajgenbaum

And then that gives us a list in rank order from the things that are 0.99 all the way down to things that are 0.00 of every drug versus every disease.

And so we come across matches that are incredible that we never could have imagined that now the algorithm is saying, you should really look at this.

You would have to, as humans, think about 75 million possibilities.

Like my lab's really good at looking at like dozens of possibilities for like one disease.

Like my lab can spend like a year and we get through a few dozen for one disease, right?

But like we could never think about like 75 million possibilities and then compare them.

And I'm not saying AI is perfect, but directionally, it's really good.

The things that are the 0.99s are way better than things that are the 0.5s.

Yeah, I guess there's two probabilities here.

I think that one is that what is the likelihood that there is a drug out of those 4,000 that could work for that disease?

And then what's the likelihood that you or anyone else is going to find it, right?

Because it's just like, A, does it exist?

And B, can you find it?

I think that A, does it exist?

uh this is obviously a really hard thing to guesstimate on but like i'm gonna say somewhere in the realm for any given disease somewhere in the realm of maybe 10 to 20 that there's something out there um and then in the realm of are you or is a team going to find it in time for you it becomes much lower than 10 to 20 likelihood right just because the the steps that have to happen right

And so for us, you know, we're going to be the organization that is going to identify and unlock as many of these drugs as possible.

So that way we don't have to be throwing Hail Marys so that like when you get diagnosed, it's, oh, wow, you have pulmonary arterial hypertension.

You should just take this medicine.

Oh, wow, you have glioblastoma.

You should take this medicine.