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Dr. David Fajgenbaum

๐Ÿ‘ค Speaker
1737 total appearances

Appearances Over Time

Podcast Appearances

Radiolab
The Medical Matchmaking Machine

Our medical team uses these same machine learning algorithms.

Radiolab
The Medical Matchmaking Machine

You can use them too, but it's important to remind them that when our medical team uses those machine learning algorithms

Radiolab
The Medical Matchmaking Machine

and they come up with something like lidocaine for breast cancer, we still then go on to do a bunch of laboratory work of lidocaine in breast cancer.

Radiolab
The Medical Matchmaking Machine

And then we think about doing the right clinical trial of lidocaine in breast cancer.

Radiolab
The Medical Matchmaking Machine

So it's not like we use the algorithm to immediately move forward into action.

Radiolab
The Medical Matchmaking Machine

We use it to then plan out what to do next.

Radiolab
The Medical Matchmaking Machine

So our feeling is that we as a nonprofit at EveryCure, we're only going to be able to go through like dozens.

Radiolab
The Medical Matchmaking Machine

I mean, if we can get to the hundreds, I would be over the moon about it.

Radiolab
The Medical Matchmaking Machine

But like there are still thousands of diseases that like could potentially benefit from our scores that we'll just never be able to get to unless it's like because the list that Matrix is spitting out is just so big.

Radiolab
The Medical Matchmaking Machine

It's so big and it's so powerful.

Radiolab
The Medical Matchmaking Machine

The thing is, when we look at the top, we are blown away by the number of promising drugs.

Radiolab
The Medical Matchmaking Machine

We're like, wow.

Radiolab
The Medical Matchmaking Machine

And actually, some of the cases, there's actually been clinical trials that have shown the drug works.

Radiolab
The Medical Matchmaking Machine

But someone stopped after the small trial because there was no way to commercialize it.

Radiolab
The Medical Matchmaking Machine

So one part is, let's make it available to the world so that other people can pursue these things that we're not able to go after.

Radiolab
The Medical Matchmaking Machine

And the other is sort of probably a little bit inspired by

Radiolab
The Medical Matchmaking Machine

Maybe we shouldn't be so paternalistic in medicine, and maybe we should allow this information to be out there.

Radiolab
The Medical Matchmaking Machine

Of course, when I say that, I do cringe just a little bit because I don't want us to create problems by putting this out there.

Radiolab
The Medical Matchmaking Machine

But it feels like the responsible thing is to share the scores.

Radiolab
The Medical Matchmaking Machine

but to appropriately caveat them and disclaim them to say, like, these are for research purposes.