Dr. David Perlmutter
Appearances
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Hi everyone, Drew Proat here. Let me share some pretty sobering statistics with you. Globally, 55 million people have been diagnosed with Alzheimer's disease, and that number is set to triple by 2050. But you might be surprised to learn that only 3 to 5% of those cases of Alzheimer's disease are driven by only genetics.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
It's such an important point because so many times when people... whether they're in the wellness world or they're just somebody who's just trying to live their best life. This is not an area they study. They may not be listening to this podcast. Anybody who's dealing with extra fat on their body and has struggled with it for a while feels that their body is working against them.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Give us the next big bucket that you often see for people that often doesn't get as much attention as diet does when it comes to cognitive decline, dementia, and Alzheimer's.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
They feel that there's something wrong with them. They feel like even some cases I've heard people – go to an extreme and feel like their body is almost punishing them. And what you're really highlighting here is that your body is doing exactly what it was designed to do. It's just, we're giving it the wrong signals.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
It's constantly preparing for winter based on the way that we're eating, living, and going about our modern lives. It reminds me of a story that I was, uh, hiking up in a glacier national park, um, up in Montana, near and by the border of Canada. And I was with a guide, and she was like, you know, there's this really cool edible berry that I want to show you. And it was about...
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
end of September, getting ready for snow season, October up there, especially at higher elevation. She said, let's go through this path over here. We went to that path and the berry bushes were there, but all the berries were gone. She's like, oh, the bears actually came in and must have eaten all the berries. They're getting ready for hibernation.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So they're eating as much fruit as possible because they're going to go hibernate over the winter. And so they need to store all that fat. And so in that same way, we're going around in our diet and
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Between the grains that we're eating, the fructose that's in our diet, the severe blood sugar dysregulation, the overproduction of insulin, we are telling our body winter is coming and we better get ready. You know, one of the things that I'm sure you've seen this too with a lot of people that follow your book, blood sugar...
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
If we look back actually and zoom out at sort of dietary trends in America, starting first with sort of Alice Waters, the sort of farm-to-table movement, the rise of sort of vegetarianism in the 60s with sort of the hippie culture and that sort of thing like that, and then coming into nowadays clean eating and then more hyper-focused areas, personalized nutrition, blood sugar
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I'd say that first as a counter to the notion of what are the big legs that support this decline would be genetics. Genetics is not that relevant. In fact, playing only about a 5% role that people say, well, I carry the APOE4 allele, therefore I'm at greater risk. But understand that that so-called Alzheimer's gene plays upon other variables that we can absolutely control.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
regulation and managing your blood sugar is a new concept for a lot of people because we're used to thinking in terms of you know good and bad right so if somebody's vegetarian they think okay meat
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And I'm not, and I know you're not, but just looking from their lens, okay, meat is bad, and then this is good, or this is good, and this is bad if somebody eats a particular way like gluten-free or whatever it might be. But blood sugar regulation and paying attention to that, it almost is like, look, any diet can work for you, and every diet could also work against you.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
There's actually a ton of products that are on the market that are called keto, that when people are using things like levels, continuous glucose monitor, they're seeing that Actually, this thing is raising my blood sugar more than anything else that I'm eating right now because it's this processed snack that's there. So I'm very excited and I'd love to get your thoughts on a personal level.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
As you've been monitoring your own blood sugar and making it make sense for you and your life and your level of activity, have you been surprised at what things might move the needle in the right or the wrong direction when it comes to your own blood sugar management?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yes. And I think it, more broadly, is great information. We can all learn personalized medicine for ourselves based upon the input from wearables these days and learn things like, I didn't realize cashews were such an issue. And they were for me, for whatever reason, eating cashews bumped up my blood sugar. I also recognized that my blood sugar was not as
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I deal with not a really good night's sleep. So a lot of correlation between the metrics of my sleep, again, as determined by wearable and what I would see on my CGM or continuous glucose monitor. And I think that's sort of the beauty of what LEVELS is doing is allowing us to see it in real time and then to make those correlations.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
But I think that what is most important is not to define the best diet for everybody. And that's been the trend. Everyone should be vegan. Everyone should be keto. Everyone should be paleo. And I think what is more valuable is to define the goals. What are we trying to achieve with our diets?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Certainly, as you well mentioned, that control over blood sugar, keeping blood sugar in check is a certainly valuable goal. If you want to take it further than keeping uric acid in check, keeping other inflammatory markers in check, all well and good, having a diet that caters to the a gut bacteria, a diet that's rich in polyphenols, antioxidants, all well and good.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
But I think these days we have the ability to personally obtain the metrics that can then reveal the value or the threat imposed by the dietary choices that we make. That's the science part. There's a social part to our dietary choices as well. And we leave that up to the individual. But all roads lead to Rome. any of the popular diets and modify them to reach our goals.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Like you say, what might have raised my blood sugar might not raise your blood sugar, but we can determine that when we're careful and we start doing a little bit of science and understand that we're all different. We all have certainly different genomes. We all live in different places. It's varying times of the year. Seasonality varies across the planet.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And perhaps most importantly, aside from our genome, our microbiomes are very different. And the array and diversity and numbers of organisms living in the gut are really influential in terms of how we interpret the foods that we eat and how it plays out in terms of measurable metrics like blood sugar, for example.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So I think gaining that information through the technology that we have as individuals, apart from what we can get in the doctor's office, I think is exceedingly valuable. And it gets back to, you know, earlier part of our conversation where we were developing, we went somewhere else.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
But we're developing a dichotomy between just the notion of sort of living your life however you want and then hoping for an Alzheimer's drug versus really beginning to embrace the notion that our choices have huge impact in terms of our brain's destiny. And that's a wedge being drawn in our society right now, really tending to...
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
really reveal how polarized we are, that the mainstream would have us believe that there's another drug down the pike coming soon enough that'll save us all, and getting excited about a drug that slows the progression by 32%. That all well and good, but I am not really interested in a drug that'll slow Alzheimer's progression by 32%.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So, you know, the point I want to make for your viewers is really quite simple. And that is if mom or dad had Alzheimer's, or if you know that you, by virtue of your 23andMe or other genetic profile, carry one or two of what are called the APOE4 alleles, which are indeed associated with increased risk for Alzheimer's, All well and good and interesting.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I'm interested in lifestyle approaches that can reverse that problem, for example, and put people back on their feet. And that is, again, in the realm of personalized medicine, what does that individual need? It's much more important to know the person who has the problem rather than understand the problem the person has.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
You were mentioning the gut bacteria earlier. I have another question for you on a personal level because people are always interested. And obviously, your experience is your own experience. It's not necessarily going to be everybody's experience. But it highlights, again, this theme of personalization. So just as you mentioned, for you, cashews, that was something that you were highlighting.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Again, just for you that you've monitored and you saw.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
No, I love them.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yeah, though you love them and I'm sure you have them occasionally and it might just mean less quantity, right? And being aware. Is there something on a gut health level that you find doesn't work for you? Like sometimes people see that, you know, even though certain types of dairies might actually could be beneficial, right? Like super high quality dairies or goat's milk or sheep's milk.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
You know, I personally know for me. Yeah, I personally know for me that... dairy, no matter how high the quality, I have to be very careful about the dose because I still am very reactionary, probably because I was on a lot of antibiotics when I was younger and it decimated a little bit of my gut bacteria.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
When it comes to your gut health, and we're also eating for our gut, are there foods that you just know that don't sit with you as well, if there are any? So I recently sat down with one of the biggest experts in the food is medicine space, and he shared some pretty fascinating information about the power of tea. Yes, that's right. Tea.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Now I grew up in a tea drinking household to say the least, but I didn't realize how beneficial tea was until I got older and dug into the incredible research. There are so many different types of teas, but the ones that I like. And the ones that this expert recommended to me are Peaks Green and Black Pu-erh Tea.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
These teas are known for having a high concentration of polyphenols, higher than many other teas on the market, and they are fermented, which means that they can support your digestion and your gut health too. Plus, they have high concentrations of antioxidants, which we could all use a little bit support to support our immune system these days.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I love sipping on Peak's green and black pu-erh teas mid-morning or after lunch when I need a little bit of a boost. They contain L-theanine, which also helps me stay focused even on my busiest days.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I really do think that it's important to be super careful about where we source our coffee and teas, and that's one of the reasons that I love Peak because they've always upheld a standard that makes me feel confident in their product. Because I'm obsessive about quality, I love that these teas are triple toxin screen for pesticides, heavy metals, and even things like mold.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
You know, for a limited time, if you're interested in getting the longevity and gut benefits of Peak Teas, they're offering my community 20% off a free starter kit of these amazing teas, plus a frother and beaker. I'm a huge fan of the beaker, by the way. Don't miss out on this incredible deal with my exclusive link. And that link is peaklife.com slash drew.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
That's P-I-Q-U-E-L-I-F-E.com slash D-H-R-U, Drew. That's me to get 20% off plus your free starter kit. Cheers to making 2025 the healthiest and most vibrant year yet with high quality teas from Peak Tea.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I would say that that's more of a cognitive prefrontal choice rather than more of an emotional or a visceral kind of a response. I don't have any real intolerances that I can experience or I have experienced and therefore know that that particular food isn't good for me. My choice is...
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
No question that having that genetic predisposition and others, presenilin-1, for example, increase your risk. But by all means, the dye isn't cast. It means that our choices, we have control over things that are really influential. And
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
come from more of an understanding in terms of the value of a particular food or the threat of a particular food or lifestyle choice or medication, you name it, in terms of the gut bacteria. Give you an example. Last week, I had surgery on my shoulder and I was given a prescription for an antibiotic and to keep the wound from being infected and made sense to me.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I mean, you know, my career started off in general surgery, then neurosurgery, and that was standard operating practice. So I know what a threat that you just mentioned it, you know, how your early life experience was. I know what a threat that is.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
You know, antibiotics, though they can save lives and are a very important part of our armamentarium, nonetheless, they are weapons of mass microbial destruction in the gut. And I like to not take it. And so far, so good. I'm four days into it. My wound looks just fine. So I think I'm going to be okay. Would there have been an upside to taking an antibiotic in terms of reducing risk of infection?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yeah, I would think. But knowing the downside, knowing the risk, knowing the relationship between Antibiotic exposure, for example, and the development of type 2 diabetes, well described. In women, antibiotic exposure is associated with an increased risk of breast cancer.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We could certainly talk about antibiotics and non-steroidal anti-inflammatories and acid-blocking medications and a host of others that are directly threatening the gut bacteria. So I think that these are choices that I make less on how it feels to me as opposed to what I understand about the science.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
taking that information and getting it out, uh, in any possible forum, like chatting with you today, that allows me to get information out that, you know, that, that would be helpful for people in terms of catering to the, the health and diversity of their gut bacteria. It's really, really important.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Matter of fact, interestingly, a study was published this morning, uh, that was sent to me by Dr. Stephen Gundry, uh, You may have heard of Dr. Gundry, has done a lot of work on lectins and a terrific cardiologist. And the study had to do with this very, very primitive tribe that's often studied in Bolivia.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
where they have what looks to be a very primitive array of bacteria in their gut, microbiome. And it looks like their microbiomes, when it's sequenced, emulates what our ancestors from thousands and thousands of years ago had in their gut. And we're actually able to determine that from looking at fossilized poop.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I think the biggest issue would be, and they're all important, don't get me wrong, but I think the biggest issue, at least in our modern world, has to do with our metabolism and elevation of our blood sugar, and therefore compromise of our ability to have insulin in the body do its job. And I think... To take a step back, back to high school biology, well, what's the importance of insulin?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We're still able to recover markers that allow us to determine what the bacteria was like. Anyway...
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
The study today said that these people who are infested with all kinds of bacteria, but beyond that, all kinds of worms and other parasites, that they demonstrate larger brains, reduced risk of cardiovascular disease, and really preservation of their bodies as they age in comparison to age-matched individuals living in modern society.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So my point is that this relationship, we've been talking about this since we started today, this relationship between what our gut bacteria are doing and their diversity is huge and extremely valuable. We're just beginning to understand it and therefore be able to tap into it as another powerful tool in the toolbox. I interviewed a Dr. Molly Fox recently.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
several years ago, a researcher who in 2013 published a report that correlated Alzheimer's risk with what's called hygiene, basically. And the marker of hygiene was looking at how many parasites were in the gut. Those countries, she looked at 100 countries around the world, those countries around the world that had poor hygiene,
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
as evidenced by higher levels of parasites in the gut, had the very lowest risk of Alzheimer's. Countries with great hygiene, countries in Northern Europe, the United States, et cetera, that are very much invested in hygiene, keeping us sterile, keeping us clean, keeping our kids from playing in the dirt, had the highest levels of Alzheimer's.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
A correlation, certainly back in 2013, just a correlation, though I've interviewed her more recently.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And now that we understand mechanisms whereby the gut bacteria are regulating what we've been talking about, our blood sugar, regulating the set point of inflammation, regulating autoimmunity, I think it becomes extremely valuable information as it relates to understanding the relationship moving forward and what we can do about it between the gut and the brain.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I think the take-home message here is to just embrace the incredible role that these bacteria and other species are playing in the gut in terms of regulating so many important aspects of our lives, whether it's our metabolism, whether it's our mood, whether it's our brain functionality moment to moment, immune system, that's for sure. Even our gene
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
expression to some degree is regulated by some of the products manufactured like short chain fatty acids by the very bacteria that live within the gut.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Maintaining balanced blood sugar levels and implementing lifestyle practices to support our gut health has so many beneficial implications for our overall health and our brain health specifically. In my conversation with Dr. Lisa Moscone, she further breaks down how what we eat is so impactful to both our metabolic health and to preventing cognitive decline.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Dr. Mosconi also shares what happens metabolically while women go through menopause and why our lifestyle practices play such a huge role in supporting our brain health, or if done incorrectly, brain dis-ease. Let's listen in.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Insulin is important for getting glucose or sugar into the cell and therefore lowering or regulating blood sugar levels. Well, all well and good, but I think that we have a tendency to be really myopic when we assign our understanding of insulin or glucose other things in the body, other metrics to a specific, uh, area to the exclusion of other functionality.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Medical detoxification.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
They'll age you.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Right? I mean, people do see it. People who eat ultra-precious diet, they see it in their skin.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
The truth is that Alzheimer's disease and all cognitive decline has largely been shown in surveys all around the world to be seen as one of the scariest things that anyone could imagine happening to themselves. And I've seen this firsthand and the devastating impact that this can have on individuals and families with my own grandfather.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Beautiful. I love that. You have a new book all about the menopause brain. Talk to us about that time in a woman's life. What is actually fundamentally going on in the brain? And I believe you also have some incredible scans that can help illustrate the message and really drive it home as well too.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And, you know, for example, we say, well, testosterone is the male hormone. You know, women need testosterone, very important. Uh, progesterone was named because it's pro gestation. It's the, you know, a female hormone that goes up during a gestation. Why would my body have progesterone receptors? I think it's important to expand less in this case, uh,
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
on what insulin does in the human body, and specifically vis-a-vis our conversation now, how does insulin relate to the brain? Well, insulin does play a role in allowing brain energetics. We'll come back to that in a moment, but it's the way that blood sugar gets into the brain glucose to ultimately lead to the powering of the brain cells, the neurons specifically.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yeah, and we're looking at a scan of her brain right now.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Right. Why some women do that.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Why other women, it's more delayed.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
It's showing a positive usage of energy inside the brain. Yes.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And in this brain, just for those that are listening, this brain has all those things, right?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yeah, there's a lot less red in the brain.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And remind us over what period of time was this?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Seven years. So these are over a seven year period that transitions slowly, slowly going from a lot of red to a lot of green, which is a 30% reduction in brain energy metabolism.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And that's really important when our Bodies become insulin resistant. We'll talk about how we get there. I guess I'm paving the way for a lot of conversation. Then that functionality, brain energetics is compromised. That's a bad thing. We can scan brains 20 years ahead of time
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Yeah, this work is phenomenal. And, you know, just to kind of connect some of the dots there, in the book you say this is not just about the ovaries. Yeah. It's about the brain, which is how science looked at it and medicine looked at it for many years, is that simply this is a woman who is no longer reproductive and that's just about the ovaries. That's about it.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And there's the lived experience of millions, billions of women.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
over the years talking about how they notice their brain changing, their body feels, a whole host of different things, often a negative association with that time. Women sharing like, here's all the negative things that I'm experiencing that I previously wasn't experiencing, which we'll chat a little bit more about that. And it also lives in this context that yes, this is the lived experience of
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
modern woman that's there. And there could be conditions that are happening in the way that we live today that are magnifying what would be associated as some of the more symptomatic issues that women are going through during this phase of life. Is that accurate?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
and determine already when there is compromised brain energetics that is the harbinger for future cognitive decline and ultimately Alzheimer's disease. And that means, tangentially, that the choices we make in our 30s, 40s, and 50s are very relevant because they, again, portend cognitive decline and full-blown Alzheimer's disease.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Please, please.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Let's jump into it.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Other things, however, that insulin does I think are very important. For example, We know that insulin is degraded in the brain. by something called, oddly enough, insulin degrading enzyme.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
In fact, you also add to that inside of the book, you say that these symptoms and this transition in a woman's life is also associated with sort of a negative sort of happiness index, right? Like they're... like that, I don't know exactly the proper term, but they report to feel not as content, not as sort of joyful during this period of time.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And then on the other side of it, you end up transitioning and feeling much better.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Let's do it. There it is. Describe this for the people that are listening.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Well, it turns out that when we're unable to stimulate adequately this insulin degrading enzyme because insulin functionality is compromised, that that same enzyme is involved in the degradation of this protein we referred to earlier called beta amyloid. So that's now a connection between insulin and beta amyloid. We know that insulin is important for, again, regulating blood sugar.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And why is that important? Because when our blood sugar is elevated, we change our proteins via something called this process of glycosylation, where proteins bind And that's an issue because not only does it change what the proteins look like in terms of their three dimensionality, but it also, because of those changes, alerts the immune system that, hey, here's a protein I've never seen before.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
It's good that your brain is stable.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And it's not so easily influenced.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
There's so much we can do today that can have a huge influence on the way that our brains will show up tomorrow and in years ahead.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And while we don't always think about the implications that things like blood sugar levels, gut health, and overall metabolic health have on our brains, I think today's episode is an excellent reminder of just how important these things are when it comes to protecting our brains and our cognitive health.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So if you like this episode, a huge favor, a huge ask, share this with someone that you know that is maybe a little bit worried or feels a little bit out of control when it comes to things like Alzheimer's or cognitive decline and a little bit of information, a little bit of knowledge, a little bit of hope that there are things that we can do today to improve our life tomorrow could make a huge difference in their life.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So share that episode with them. And if you want to hear the full length version of any of these conversations featured today, Dr. David Perlmutter and Dr. Lisa Moscone, you can find those links in the show note episodes in your app. Until next time, Drew Perlmutter signing off. Thank you for listening in.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And what happens? The immune system gets activated and inflammation gets turned on. And inflammation is really a central player in what degrades the brain in Alzheimer's. So
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
The point I'm making then is regulation, balancing our blood sugar, keeping our blood sugar under control is, while everything is important, I think that might well be perhaps the most important issue in terms of what throws the widest net, in terms of for your viewers, what they need to pay attention to, that this blood sugar regulation is in the front row.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
who I took care of while he was going through his own Alzheimer's diagnosis. But we know now that there is so much more that can be done to support our brain health, as well as reduce our risk of developing Alzheimer's disease and dementia.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
and that we need to do everything we can getting back to diet. And I know you wanted to move past that, but I chose not to because it's so important, something we all make choices about every single day, unless we're fasting, of course. And
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Everything we can with reference to diet to keep blood sugar levels under control, basically lower than they might otherwise be these days, I think is very relevant. Utilizing things like continuous glucose monitoring, checking our blood for ketones, being really aware of fructose in the diet.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So many things that influence blood sugar, our sleep patterns, our exercise patterns, sleep as we measure with our wearable devices, all of these things play into balancing blood sugar levels. And the brain is exquisitely sensitive to its provision of its fuel, which is basically glucose. And when that's compromised, when that is threatened, that really does set the stage for future decline.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I'm glad that you doubled down on the diet. I did want to cover diet. I was going to cover a few other things, but I'm glad you actually forced it in the direction that you wanted to go in because it's just another reminder that just like we say, you can't exercise your way out of a bad diet. If you're serious about brain health, you cannot approach the topic without thinking
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
thinking about blood sugar regulation. And I think that's an important message for our listeners. And it's a hopeful one because that's actually something that's largely in most people's control and will continue to be in their control as they start to use wearables like CGMs. And I know you're affiliated and I'm affiliated with a company that's doing some great stuff in that space.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We'll chat about them a little later on. I'm glad you doubled down because I think that is just an important thing for everybody to remember is that we're looking for sometimes the right supplement in the traditional world of medicine. It might be actually what medicines are there that you covered earlier, but it really has to come back to core blood sugar regulation.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
While we're on that topic, you're not just talking about sugar. and high levels of sugar in the diet or in added sugar in the foods that are there, even for people that consider themselves quite healthy, there's other forms of things that are regularly part of our lifestyle today, even in the world of modern wellness food, that are consistently throwing off our ability to regulate our blood sugar.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
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Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And in today's compilation episode, I'm talking with board-certified neurologist and best-selling author, Dr. David Perlmutter, about the crucial role of blood sugar regulation in preventing Alzheimer's disease. I'm also speaking with Dr. Lisa Moscone, an associate professor of neuroscience in neurology and radiology at Cornell Medicine.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
She'll tell you it's true. Cozy Earth's bamboo sheet set has completely transformed my sleep and created many relaxing, cozy moments with my wife. We actually love it so much, we put it in our guest bedroom too. These sheets are ridiculously soft, like sleeping on a cloud.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
They're moisture-wicking, breathable, and temperature-regulating, so I stay cool at night without waking up overheated, which means I'm not tossing and turning all night, which is huge. Switching to Cozy Earth was also important to me because they avoid toxic chemicals like PFAs and plastics, which are found in so many household materials and sheets and bedding.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
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Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
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Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
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Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Well, that act the same as sugar in the body. Let me just take that back a little bit. And one of the surprising things that I found that really plays such a central role in blood glucose regulation is a different sugar called fructose. You know, the amount of fructose we are consuming now is, I think, breathtaking, seeing that table sugar is 50% glucose and 50% fructose.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
That's what sucrose or table sugar is. But now we're seeing our foods peppered, wrong term, sweetened with what is called high fructose corn syrup, which might be 52% fructose, but in reality, maybe as high as 90% fructose.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Now, the messaging on fructose over the years was, hey, that's a better choice than eating glucose because fructose, unlike glucose, does not elicit this insulin response that we just spoke about. And while that may be true in the short term, we know that ultimately through its unique metabolism that fructose is extremely threatening to
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
to the way that insulin works in the body and ultimately leads to elevation of our blood sugar, elevation of our blood pressure, dysregulation of our lipids, increased risk of obesity, increased risk of other metabolic issues. So we've been told that fructose is a safer sugar. Even the American Diabetes Association did until quite recently recommended fructose
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
as an alternative to glucose or highly refined carbohydrates in general. So I think we now understand, and we'll get to this later, that through its production of something called uric acid, that fructose is a powerful threat for our metabolism, therefore elevation of blood sugar, and then this increased risk of insulin resistance that we talked about just a moment ago. But you know,
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
and the director of the Women's Brain Initiative and the Alzheimer's Prevention Clinic at New York Presbyterian Hospital. Dr. Moscone and I talk about the impact of glucose metabolism on brain health, particularly in menopause. But first, let's dive into my conversation with Dr. David Perlmutter.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
I think that we could take this conversation to a lot of places. We can take it to the gut bacteria because we know that the signals sent out by our gut bacteria have a huge role to play in regulating our metabolism. There is well-described changes that can occur in the gut bacteria that pave the way for insulin resistance. And in fact, we know that
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
that is a direct response to the various foods that we eat. But I think interestingly, we can look at how these changes in our gut bacteria brought on by, for example, consumption of fructose and therefore leading to higher levels of insulin and blood sugar may have been in our hunter-gatherer days quite adaptive. Because think about it, when did we eat fructose? When did we have fruit sugar?
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We had it when the fruit was ripe. And before modern agriculture, fruit is ripe in the late summer, early fall, signaling to us that winter is coming. Winter, a time of caloric scarcity. So fructose changes our gut bacteria such that it prepares us for winter because our gut bacteria get the fructose signal and say, hey, winter is coming.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We need to change metabolism here and start storing fat and reduce the burning of fat so that we keep it around. We actually have to make more glucose, a process called gluconeogenesis. So it's the response that we get from fructose, not only in terms of our gut bacteria, but also in terms of what has created the downstream metabolism of fructose, which is uric acid.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
Uric acid is the danger signal saying winter's coming, not going to be a lot of food. You'd better make fat. You'd better store fat because you're We have higher levels of uric acid because of a unique series of mutations that occurred in our primate ancestors 14 to 18 million years ago, whereby we have much higher levels of uric acid.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
So those ancestors in our primate lineage who had those mutations survived. And now you and I and every other human walking the planet has an... and increased production of this uric acid such that we make fat, we store fat, our blood pressure is at risk for being higher.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
We develop non-alcoholic fatty liver disease and we develop dyslipidemia, higher levels of LDL and cholesterol because these were actually protective of us in the day. So what I'm describing then is what is called an evolutionary environmental mismatch, where in our past, these mutations, these changes to our metabolism allowed our survival.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
But now, because of the different environment being pounded by fructose day in and day out, lack of restorative sleep, lack of enough exercise. You know, we'll talk about these things. And, you know, challenges our genome.
Dhru Purohit Show
Why Blood Sugar Regulation is a Key Part of Alzheimer’s Prevention
And it's really, I think, the fundamental of the so-called paleo movement that we really need to respect our paleolithic genome and give it the signals that we can control that it wants in order to keep us healthy and allow us to survive, allow us to procreate, and allow us to be disease resistant.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Well, I think what's interesting about that is that when I've been in the kind of Alzheimer's advocacy space for 20 years, because my dad was diagnosed in 2003, and lifestyle was not a part of the conversation when he was originally diagnosed.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
And then as I started researching it as a reporter and started then looking at women and trying to understand what was happening in women, I said, is there anything women... Is it lifestyle connected? Is there anything we're doing, how we live? Is it... Menopause, any of these things that everybody's like, no, no, lifestyle has nothing to do with any of this.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Jump to today, in the last five years, there's been a sea change around how we talk about Alzheimer's, about saying now you have people saying, well, maybe half of these cases could be preventable due to lifestyle choices made early on, right? What you're talking about. That was when I started, it was only plaques and tangles, plaques and tangles, right? That's tau, plaques and tangles.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Right. But no one spoke about the importance of exercise. Nobody spoke about diet. Nobody spoke about nutrition in the brain. So I think this is a sea change in the Alzheimer's space. Nobody even talked about prevention of Alzheimer's. We opened the first women's Alzheimer's prevention center at the Cleveland Clinic. That's right. And everybody's like, you can't say that. And I was like, why not?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yeah, but now you can.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
When we talk about women and Alzheimer's, so it disproportionately, as I said, Alzheimer's disproportionately impacts women, but also disproportionately impacts black and brown women, right? And so, so many people don't have access to really what you're talking about. You know, some of these more kind of concierge medicine,
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
approaches, looking at biomarkers and looking at, so I'm really interested in how to democratize all of this to make it accessible to people who don't have money, who might be in maternal health deserts, who might be in just health deserts, period. So with the prevention center, I'm always looking at how do we bring this kind of home? How do we bring this, the education to people?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
How do we bring doctors who can talk about this in a way that people aren't scared?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
I think the conversation, I do a lot of work around how do you speak about this in a way that people can go, oh, I don't have to be so scared. Oh, maybe I could do this today. Maybe I could do this tomorrow. Bringing it kind of to Main Street is the challenge.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Or women's health or menopause. But this is why I think when I talk about women's health, it starts by also changing the way medicine is taught in schools, right? It's by incorporating... So many doctors said, well, I had an hour about menopause. I never even talked about perimenopause, much less postmenopausal women. That was not even in the textbook.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
You're talking about a sea change, not only with doctors who are practicing, but for those coming into the space. And then also when we talk about women's health or when we talk about Alzheimer's, getting people interested in working in that space, in the geriatric space, right? Geriatric psychiatrists, geriatric doctors. It's not young people going into orthopedics. It's not sexy.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
They're going into orthopedics. Like my daughter. That's what she wants to do. Orthopedics.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Because that's where the money is, right? And so this is a challenge on so many levels. It's a challenge on how do we talk about it? How do we bring it home to Main Street? How do we change medical schools? How do we bring doctors who are working up to date? How do we make it enticing to go into this space as we're an aging country?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
In California, I did a big report for Gavin Newsom about what does California, which is an aging state, you don't think of California that way, what do we need to do to be ready for the tsunami of baby boomers who are going to get Alzheimer's and dementia? We're not ready. We're not ready as a nation. We don't have caregivers. which also disproportionately falls on women.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
So I think it's a exciting space to be in, but it's an urgent space. It is, yeah.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
I saw on there that you have like you could gift it, right? I was like, okay, well, that's actually something that's an interesting concept. By the time you finish buying somebody flowers or coffee, you could add it. No coffee for you for the next year.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yeah. Absolutely. That's what I'm curious about.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yeah, let's start with the good news. I'm not going to die right now.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
But I want that to be better.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yes. I want to be, I have grandchildren. Yeah. I have, you know, adult children. I want to be around for them. And I don't, I think that's the other thing, watching a parent or two parents. My mother ended up with lots of strokes too later in life. And I think being a caregiver for two parents. Mm-hmm. is a lot.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Emotionally, financially, physically, spiritually, in every way, right? And then I think once you've watched that up close, you think about yourself. And if you have children, you think about, okay, well- How do I keep myself healthy? How do I keep myself so that my children- Don't have to do that. don't have to do that.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Maybe they're not capable of doing that, or maybe they don't have the money to do that, or maybe they're not in the same town. There's all these things. So I think to myself, how can I be as independent for as long as I can, be as strong as I can? So when I go to the gym now, actually, I say to the trainer, I said, give me an exercise that can help me with my overhead compartment in the plane.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
I want to lift the bag in the overhead compartment. Right. Give me an exercise. I have a granddaughter who weighs 30-some pounds. You want to pick her up. I want to pick her up. I want to walk around with her. I don't want to say when she says, Mama G, lift me up, lift me up. I don't want to go, oh, I can't. I want to be able to lift her up and then the next one up and the next one.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
So when I go to the gym today, I'm looking for- To be functional. To be functional, yeah. To be able to be strong for those things, to be independent for my kids so that they're not overwhelmed. Because I found it overwhelming to be a caregiver. Yeah.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Oh, yeah. We're going back to my test now. Right. We're going to go to the bad news now. My son said, you're not really going to talk about your own blood tests on the thing, are you? I was like, yeah, actually, I think I am.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
You can get me to 50.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
So why would I have low levels of inflammation?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Oh, I don't have low.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
I don't want to be on that trend.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
But we don't know what it is.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
I had high levels of mercury?
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Oh my gosh, I thought I had low levels of mercury.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Okay, so no more swordfish for me.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
It's no more tuna. Oh, my favorite. I don't like tuna, but I do like swordfish. Swordfish is amazing. It is one of the worst.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Oh, I'm not a big, I don't like shark at all.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Swordfish at the Ivy.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
You're going to hurt me. This is going to be a hard show for me.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Okay, swordfish, bye-bye.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Well, actually Richard Isaacson did it. So I don't know which test he did. Did you have OE4? No, I don't.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Right, so I need to eat more meat.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Maybe you do have- I definitely have some feeling of gluten sensitivity. Yeah.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Okay, so I'm going to come back. We're going to retest all of these things. We're going to change it. I'm going to come back and see how old I am and whether I actually have done better on my blood tests. That would be interesting. Under 60, under 60. Under 60, I know. I want to get to 50.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yes. In my mind, I'm like 45. Yeah.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Then I always wonder, like, you know, a lot of times you do this and they're like, go to this doctor, go to this doctor, go to this. And I'm like, oh, you know, then it's like, it's a time issue. But I know that it's, I mean, I will do it. I know.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Yeah, no, I don't want that.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
So people always talk about that. Do you want to know if you have the Alzheimer's gene? Do you want to know if you can find it? Because then what? As long as we have no cure, is that actually going to freak people out? Is that going to be helpful in any way? And I think this is a debate going on with doctors. Right, goes on. I hear it a lot. Right. But people are like, I don't want to know.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
That's not going to be helpful to me until we find a cure.
The Dr. Hyman Show
Dementia Is Skyrocketing—Here’s How to Protect Your Brain NOW
Which I totally also understand.