Dr. Eric Verdin
๐ค SpeakerAppearances Over Time
Podcast Appearances
Yes. A typical NAD infusion costs about $700. There are studies showing what happens when you inject NAD intravenously. It goes to your liver and it is cleaved into nicotinamides and ADP ribose. Now, the nicotinamide is essentially niacin. You can buy this for 20 cents or whatever. So this $700 injection, I really have no idea. Actually, no one has any idea what happens to it.
Yes. A typical NAD infusion costs about $700. There are studies showing what happens when you inject NAD intravenously. It goes to your liver and it is cleaved into nicotinamides and ADP ribose. Now, the nicotinamide is essentially niacin. You can buy this for 20 cents or whatever. So this $700 injection, I really have no idea. Actually, no one has any idea what happens to it.
Most of it is likely very quickly degraded.
Most of it is likely very quickly degraded.
Most of it is likely very quickly degraded.
Well, niacin, as you know, will activate these flushing receptors. This was one of the limiting use of niacin as a drug. But cholesterol lowering a few decades ago, people had some flushing issues. It's the same thing that you're feeling when you're taking intravenous nicotinamides.
Well, niacin, as you know, will activate these flushing receptors. This was one of the limiting use of niacin as a drug. But cholesterol lowering a few decades ago, people had some flushing issues. It's the same thing that you're feeling when you're taking intravenous nicotinamides.
Well, niacin, as you know, will activate these flushing receptors. This was one of the limiting use of niacin as a drug. But cholesterol lowering a few decades ago, people had some flushing issues. It's the same thing that you're feeling when you're taking intravenous nicotinamides.
That's the prediction. And that's what we... Although, you know, there's evidence that CD38 inhibition or deletion actually increases lifespan. So that might be one way to put back this whole pathway in the context of longevity.
That's the prediction. And that's what we... Although, you know, there's evidence that CD38 inhibition or deletion actually increases lifespan. So that might be one way to put back this whole pathway in the context of longevity.
That's the prediction. And that's what we... Although, you know, there's evidence that CD38 inhibition or deletion actually increases lifespan. So that might be one way to put back this whole pathway in the context of longevity.
It's a tough one. I tell people, you know, if you want to- In five minutes or less. Okay, so I'll start first. I think before taking any supplement, I think people should optimize the rest of their lifespan because there's nothing, you know, if you have a wound that's infected with a bacteria, you don't put a Band-Aid on it.
It's a tough one. I tell people, you know, if you want to- In five minutes or less. Okay, so I'll start first. I think before taking any supplement, I think people should optimize the rest of their lifespan because there's nothing, you know, if you have a wound that's infected with a bacteria, you don't put a Band-Aid on it.
It's a tough one. I tell people, you know, if you want to- In five minutes or less. Okay, so I'll start first. I think before taking any supplement, I think people should optimize the rest of their lifespan because there's nothing, you know, if you have a wound that's infected with a bacteria, you don't put a Band-Aid on it.
Very few people do this. So the next step would be to have, once you've optimized all of this the best you can, and I think about them as buckets. And I agree with you, by the way. Because a lot of people will go to supplements, they don't want to do any of the other things, and they're missing the really powerful stuff. The reason I'm making this point so strongly is that
Very few people do this. So the next step would be to have, once you've optimized all of this the best you can, and I think about them as buckets. And I agree with you, by the way. Because a lot of people will go to supplements, they don't want to do any of the other things, and they're missing the really powerful stuff. The reason I'm making this point so strongly is that
Very few people do this. So the next step would be to have, once you've optimized all of this the best you can, and I think about them as buckets. And I agree with you, by the way. Because a lot of people will go to supplements, they don't want to do any of the other things, and they're missing the really powerful stuff. The reason I'm making this point so strongly is that
we do not have and will not have for the next 20 years an anti-aging medicine or supplement that is better than physical activity. And mark my words, for 20 years, in 20 years, we will still not have something that works as well as physical activity.
we do not have and will not have for the next 20 years an anti-aging medicine or supplement that is better than physical activity. And mark my words, for 20 years, in 20 years, we will still not have something that works as well as physical activity.
we do not have and will not have for the next 20 years an anti-aging medicine or supplement that is better than physical activity. And mark my words, for 20 years, in 20 years, we will still not have something that works as well as physical activity.