Dr. Eric Verdin
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Podcast Appearances
Yeah, so as I mentioned, there's loss of mitochondrial number, there's loss of mitochondrial function, and there's loss of mitochondria key metabolites like NAD. And so I think when I think about what can you do, it ranges from lifestyle intervention all the way down to some of the drugs that we're actually working on.
Yeah, so as I mentioned, there's loss of mitochondrial number, there's loss of mitochondrial function, and there's loss of mitochondria key metabolites like NAD. And so I think when I think about what can you do, it ranges from lifestyle intervention all the way down to some of the drugs that we're actually working on.
So the two ways in which I think you can maximize your mitochondrial function as you age is fasting. And fasting, as I mentioned earlier, activates a process called autophagy, which means self-eating. And the beauty of autophagy
So the two ways in which I think you can maximize your mitochondrial function as you age is fasting. And fasting, as I mentioned earlier, activates a process called autophagy, which means self-eating. And the beauty of autophagy
So the two ways in which I think you can maximize your mitochondrial function as you age is fasting. And fasting, as I mentioned earlier, activates a process called autophagy, which means self-eating. And the beauty of autophagy
when you're fasting is that your body is able to sort through the garbage and the well-functioning mitochondria to discard the poorly functioning mitochondria and to keep the ones that are most efficient. So the process called mitophagy. So intermittent fasting, I think is part of the ability that your body has to shift between feeding and fasting is a process that we call metabolic flexibility.
when you're fasting is that your body is able to sort through the garbage and the well-functioning mitochondria to discard the poorly functioning mitochondria and to keep the ones that are most efficient. So the process called mitophagy. So intermittent fasting, I think is part of the ability that your body has to shift between feeding and fasting is a process that we call metabolic flexibility.
when you're fasting is that your body is able to sort through the garbage and the well-functioning mitochondria to discard the poorly functioning mitochondria and to keep the ones that are most efficient. So the process called mitophagy. So intermittent fasting, I think is part of the ability that your body has to shift between feeding and fasting is a process that we call metabolic flexibility.
And I think it is really an integral part of health So I encourage people to, you know, to incorporate this into their daily routine.
And I think it is really an integral part of health So I encourage people to, you know, to incorporate this into their daily routine.
And I think it is really an integral part of health So I encourage people to, you know, to incorporate this into their daily routine.
Well, yes, that's one way to do it, actually. And, you know, right now we're at the stage where there are a whole bunch of different fasting modalities have been developed. explored and tested. And I don't think there's clear evidence that any of them is more beneficial than another. Some people will do, you know, a deep fast every three months. Some people will do some fasting every day.
Well, yes, that's one way to do it, actually. And, you know, right now we're at the stage where there are a whole bunch of different fasting modalities have been developed. explored and tested. And I don't think there's clear evidence that any of them is more beneficial than another. Some people will do, you know, a deep fast every three months. Some people will do some fasting every day.
Well, yes, that's one way to do it, actually. And, you know, right now we're at the stage where there are a whole bunch of different fasting modalities have been developed. explored and tested. And I don't think there's clear evidence that any of them is more beneficial than another. Some people will do, you know, a deep fast every three months. Some people will do some fasting every day.
I think there are, we're still at the stage where these different modalities are being compared and trying to decide what is the best way. But Any of them is better than none. That would be the rule that I would. Practically, for me, I do a five-day fast every three months.
I think there are, we're still at the stage where these different modalities are being compared and trying to decide what is the best way. But Any of them is better than none. That would be the rule that I would. Practically, for me, I do a five-day fast every three months.
I think there are, we're still at the stage where these different modalities are being compared and trying to decide what is the best way. But Any of them is better than none. That would be the rule that I would. Practically, for me, I do a five-day fast every three months.
And then I do sort of what people call restricted time feeding, which means I try not to eat for 12 to 16 hours every day so that I at least have a period of fasting. There are also a number of interesting supplements that are emerging that are supplements or drugs.
And then I do sort of what people call restricted time feeding, which means I try not to eat for 12 to 16 hours every day so that I at least have a period of fasting. There are also a number of interesting supplements that are emerging that are supplements or drugs.
And then I do sort of what people call restricted time feeding, which means I try not to eat for 12 to 16 hours every day so that I at least have a period of fasting. There are also a number of interesting supplements that are emerging that are supplements or drugs.